Evidence map›Paper›PMID 37431566›Full record

ArticleJournal of biophotonics2023

Multispectral optoacoustic tomography is more sensitive than micro-computed tomography for tracking gold nanorod labelled mesenchymal stromal cells.

Alejandra Hernandez Pichardo, James Littlewood, Arthur Taylor, Bettina Wilm, Raphaël Lévy, Patricia Murray

Open access · hybridAbstract read
In one paragraph

Article in Journal of biophotonics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Alejandra Hernandez PichardoDepartment of Molecular Physiology and Cell Signalling, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
James LittlewoodDepartment of Molecular Physiology and Cell Signalling, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Arthur TaylorDepartment of Molecular Physiology and Cell Signalling, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Bettina WilmDepartment of Molecular Physiology and Cell Signalling, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Raphaël LévyUniversité Sorbonne Paris Nord and Université de Paris, INSERM, LVTS, Paris, France.
Patricia MurrayDepartment of Molecular Physiology and Cell Signalling, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.ORCID https://orcid.org/0000-0003-1316-148X
University of Liverpool · GBInserm · FR

Funding

European CommissionEuropean Research Council 856478European Research Council (ERC) 856478Marie Skłodowska-Curie grant 813839Wellcome Trust 208389
6 · The paper itself

Abstract

Tracking the fate of therapeutic cell types is important for assessing their safety and efficacy. Bioluminescence imaging (BLI) is an effective cell tracking technique, but poor spatial resolution means it has limited ability to precisely map cells in vivo in 3D. This can be overcome by using a bimodal imaging approach that combines BLI with a technique capable of generating high-resolution images. Here we compared the effectiveness of combining either multispectral optoacoustic tomography (MSOT) or micro-computed tomography (micro-CT) with BLI for tracking the fate of luciferase

Indexed as

GoldMesenchymal Stem CellsNanotubesPhotoacoustic TechniquesX-Ray MicrotomographyAnimalsCell TrackingHumansLuminescent MeasurementsMiceStaining and LabelingTomographyGoldbioluminescencecell trackinggold nanorodsmesenchymal stromal cellsmicro-CTmultispectral optoacoustic tomography

Identifiers

PMID37431566
PMCPMC7616740
OpenAlexW4383872439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.