Evidence map›Paper›PMID 37431478›Full record

ArticleBioImpacts : BI2023

Synthesis, characterization, and evaluation of pH-sensitive doxorubicin-loaded functionalized graphene oxide in osteosarcoma cells.

Forough Alemi, Masomeh Maleki, Mostafa Mir, Abbas Ebrahimi-Kalan, Mojtaba Zarei, Bahman Yousefi, Nadereh Rashtchizadeh

Abstract read
In one paragraph

Article in BioImpacts : BI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Forough AlemiStudent Research Committee, Tabriz University of medical sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0003-2055-1961
Masomeh MalekiDepartment of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Mostafa MirMetabolic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Abbas Ebrahimi-KalanDepartment of Neurosciences and cognition, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Mojtaba ZareiMolecular Medicine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Bahman YousefiStudent Research Committee, Tabriz University of medical sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0002-4220-1527
Nadereh RashtchizadehStudent Research Committee, Tabriz University of medical sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0003-2878-3847

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Doxorubicin (DOX) is one of the most common drugs in cancer treatment. However, its partial solubility along with the high incidence of side effects remains a challenge to tackle. To address these issues, we designed a formulation based on graphene oxide (GO) and used it as an anticancer drug delivery system. Methods: The physical and chemical properties of the formulation were studied using FTIR, SEM, EDX, Mapping, and XRD. Release studies in the Results: Conclusion: In summary, our results suggest a DOX-loaded graphene oxide carrier as a potential platform for targeting cancer cells.

Indexed as

DoxorubicinGO nanosheetOsteosarcomaQuaternized imidazoliumTris-modified GO

Identifiers

PMID37431478
PMCPMC10329751

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.