Evidence map›Paper›PMID 37431472›Full record

ArticleJCPP advances2021

Identification of the most indicative and discriminative features from diagnostic instruments for children with autism.

Sanna Stroth, Johannes Tauscher, Nicole Wolff, Charlotte Küpper, Luise Poustka, Stefan Roepke, Veit Roessner, Dominik Heider, Inge Kamp-Becker

Abstract read
In one paragraph

Article in JCPP advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Differentiation of autism spectrum disorder and mood or anxiety disorder.Autism : the international journal of research and practice · 2022
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sanna StrothDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy Philipps University of Marburg Marburg Germany.ORCID https://orcid.org/0000-0002-0266-173X
Johannes TauscherDepartment of Mathematics and Computer Science Philipps University of Marburg Marburg Germany.
Nicole WolffDepartment of Child and Adolescent Psychiatry Faculty of Medicine TU Dresden Dresden Germany.
Charlotte KüpperDepartment of Psychiatry Campus Benjamin Franklin Charité-Universitätsmedizin Berlin Berlin Germany.
Luise PoustkaDepartment of Child and Adolescent Psychiatry and Psychotherapy University Medical Center Göttingen Göttingen Germany.
Stefan RoepkeDepartment of Psychiatry Campus Benjamin Franklin Charité-Universitätsmedizin Berlin Berlin Germany.
Veit RoessnerDepartment of Child and Adolescent Psychiatry Faculty of Medicine TU Dresden Dresden Germany.
Dominik HeiderDepartment of Mathematics and Computer Science Philipps University of Marburg Marburg Germany.
Inge Kamp-BeckerDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy Philipps University of Marburg Marburg Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diagnosing autism spectrum disorder (ASD) is complex and time-consuming. The present work systematically examines the importance of items from the Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule (ADOS) in discerning children with and without ASD. Knowledge of the most discriminative features and their underlying concepts may prove valuable for the future training tools that assist clinicians to substantiate or extenuate a suspicion of ASD in nonverbal and minimally verbal children. Methods: In two samples of nonverbal ( Results: For nonverbal children, the RF classifier indicated social orientation to be most powerful in differentiating ASD from non-ASD cases. In minimally verbal children, we find language/speech peculiarities in combination with facial/nonverbal expressions and reciprocity to be most distinctive. Conclusion: Based on machine learning strategies, we carve out those symptoms of ASD that prove to be central for the differentiation of ASD cases from those with other developmental or mental disorders (high specificity in minimally verbal children). These core concepts ought to be considered in the future training tools for clinicians.

Indexed as

ADI‐RADOSautism spectrum disorderdiagnostic‐gold‐standarddifferential‐diagnosismachine learning

Identifiers

PMID37431472
PMCPMC10242833

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.