Evidence map›Paper›PMID 37431400›Full record

ArticleJCPP advances2021

Intergenerational transmission of parental neuroticism to emotional problems in 8-year-old children: Genetic and environmental influences.

Helga Ask, Espen M Eilertsen, Line C Gjerde, Laurie J Hannigan, Kristin Gustavson, Alexandra Havdahl, Rosa Cheesman, Tom A McAdams, John M Hettema, Ted Reichborn-Kjennerud and 2 more

Open access · goldAbstract read
In one paragraph

Article in JCPP advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Helga AskDepartment of Mental Disorders Norwegian Institute of Public Health Oslo Norway.ORCID https://orcid.org/0000-0003-0149-5319
Espen M EilertsenPROMENTA Research Center University of Oslo Oslo Norway.
Line C GjerdeDepartment of Mental Disorders Norwegian Institute of Public Health Oslo Norway.
Laurie J HanniganNic Waals Institute Lovisenberg Diaconal Hospital Oslo Norway.
Kristin GustavsonDepartment of Mental Disorders Norwegian Institute of Public Health Oslo Norway.
Alexandra HavdahlDepartment of Mental Disorders Norwegian Institute of Public Health Oslo Norway.ORCID https://orcid.org/0000-0002-9268-0423
Rosa CheesmanSocial Genetic & Developmental Psychiatry Centre King's College London London UK.
Tom A McAdamsSocial Genetic & Developmental Psychiatry Centre King's College London London UK.ORCID https://orcid.org/0000-0002-6825-3499
John M HettemaTexas A&M Health Science Center Bryan Texas USA.
Ted Reichborn-KjennerudDepartment of Mental Disorders Norwegian Institute of Public Health Oslo Norway.
Fartein A TorvikCentre for Fertility and Health Norwegian Institute of Public Health Oslo Norway.
Eivind YstromDepartment of Mental Disorders Norwegian Institute of Public Health Oslo Norway.ORCID https://orcid.org/0000-0003-4390-6171
Norwegian Institute of Public Health · NOKing's College London · GBLovisenberg Diakonale Høgskole · NOTexas A&M Health Science Center · USUniversity of Oslo · NO

Funding

Wellcome Trust
6 · The paper itself

Abstract

Background: Children of parents with high levels of neuroticism tend to have high neuroticism themselves as well as increased risk of experiencing symptoms of anxiety and depression. It is not yet clear how much of this link is attributable to a potential effect of parent on child (e.g., via a socializing effect) versus to shared genetic risk. We aimed to determine whether there is an intergenerational association after accounting for genetic transmission and assortative mating. Methods: We used data from the Norwegian Mother, Father and Child Cohort Study including 11,088 sibling pairs in the parental generation, their partners ( Results: After accounting for assortative mating in parents (phenotypic Conclusions: These results are consistent with direct effects between maternal and offspring neuroticism and between maternal neuroticism and offspring symptoms of anxiety and depression. Further understanding of these intergenerational processes will require an adequate model of how these constructs (neuroticism, anxiety and depression) relate to each other within generations.

Indexed as

anxietychildren‐of‐twinsdepressionMoBaneuroticism

Identifiers

PMID37431400
PMCPMC10242898
OpenAlexW3215792647

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.