Evidence map›Paper›PMID 37431387›Full record

ArticleJCPP advances2022

Developmental co-occurrence of psychopathology dimensions in childhood.

Andrea G Allegrini, Toos van Beijsterveldt, Dorret I Boomsma, Kaili Rimfeld, Jean-Baptiste Pingault, Robert Plomin, Meike Bartels, Michel G Nivard

Open access · goldAbstract read
In one paragraph

Article in JCPP advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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  9. Continuity of Psychopathology Throughout Adolescence and Young Adulthood.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Andrea G AllegriniSocial, Genetic and Developmental Psychiatry Centre Institute of Psychiatry Psychology and Neuroscience King's College London London UK.ORCID https://orcid.org/0000-0003-4048-4292
Toos van BeijsterveldtDepartment of Biological Psychology Faculty of Behavioral and Movement Sciences Vrije Universiteit Amsterdam Amsterdam THE NetherLand Eroupe.
Dorret I BoomsmaDepartment of Biological Psychology Faculty of Behavioral and Movement Sciences Vrije Universiteit Amsterdam Amsterdam THE NetherLand Eroupe.ORCID https://orcid.org/0000-0002-7099-7972
Kaili RimfeldSocial, Genetic and Developmental Psychiatry Centre Institute of Psychiatry Psychology and Neuroscience King's College London London UK.ORCID https://orcid.org/0000-0001-5139-065X
Jean-Baptiste PingaultSocial, Genetic and Developmental Psychiatry Centre Institute of Psychiatry Psychology and Neuroscience King's College London London UK.
Robert PlominSocial, Genetic and Developmental Psychiatry Centre Institute of Psychiatry Psychology and Neuroscience King's College London London UK.
Meike BartelsDepartment of Biological Psychology Faculty of Behavioral and Movement Sciences Vrije Universiteit Amsterdam Amsterdam THE NetherLand Eroupe.
Michel G NivardDepartment of Biological Psychology Faculty of Behavioral and Movement Sciences Vrije Universiteit Amsterdam Amsterdam THE NetherLand Eroupe.
King's College London · GBAmsterdam University of Applied Sciences · NLVrije Universiteit Amsterdam · NL

Funding

NIMH Center Repository Supporting Stem Cell ResearchU24MH068457 · NIMH · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI BRZUSTOWICZ, LINDA M, KNOWLES, JAMES A · 2003 to 2024
$213.8M
Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife2)R01AG046938 · NIA · UNIVERSITY OF COLORADO · PI REYNOLDS, CHANDRA A, WADSWORTH, SALLY J · 2015 to 2024
$18.5M
Genomics of Developmental Trajectories in TwinsRC2MH089995 · NIMH · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HUDZIAK, JAMES J. · 2009 to 2010
$3.8M
Dissecting the Multivariate Genetic Architecture of Psychiatric DiseasesR01MH120219 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI NIVARD, MICHEL GUILLAUME, TUCKER-DROB, ELLIOT MAX · 2020 to 2024
$3.3M
DEVELOPMENTAL TWIN STUDY: ATTENTION, AGGRESSION, AFFECTR01MH058799 · NIMH · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI HUDZIAK, JAMES J. · 2000 to 2004
$1.7M
NIA NIH HHS R01 AG046938NIMH NIH HHS R01 MH058799NIMH NIH HHS R01 MH120219NIMH NIH HHS RC2 MH089995NIMH NIH HHS U24 MH068457
6 · The paper itself

Abstract

Background: Comorbidity between psychopathologies may be attributed to genetic and environmental differences between people as well as causal processes within individuals, where one pathology increases risk for another. Disentangling between-person (co)variance from within-person processes of psychopathology dimensions across childhood may shed light on developmental causes of comorbid mental health problems. Here, we aim to determine whether and to what extent directional relationships between psychopathology dimensions within-person, and between individuals within families, play a role in comorbidity. Methods: We conducted random intercepts cross-lagged panel model (RI-CLPM) analyses to unravel the longitudinal co-occurrence of child psychopathology dimensions, jointly estimating between-person and within-person processes from childhood to early adolescence (age 7-12). We further developed an extension of the model to estimate sibling effects within-family (wf-RI-CLPM). Analyses were separately conducted in two large population-based cohorts, TEDS and NTR, including parent-rated measures of child problem behaviours based on the SDQ and CBCL scales respectively. Results: We found evidence for strong between-person effects underlying the positive intercorrelation between problem behaviours across time. Beyond these time-varying within-person processes accounted for an increasing amount of trait variance, within- and cross-trait, overtime in both cohorts. Lastly, by accommodating family level data, we found evidence for reciprocal directional influences within sib-pairs longitudinally. Conclusions: Our results indicate that within-person processes partly explain the co-occurrence of psychopathology dimensions across childhood, and within sib-pairs. Analyses provided substantive results on developmental processes underlying comorbidity in behavioural problems. Future studies should consider different developmental timeframes to shed more light on the processes contributing to developmental comorbidity.

Indexed as

comorbiditydevelopmentgenetic and environmental effectspsychopathologysibling effects

Identifiers

PMID37431387
PMCPMC10242955
OpenAlexW4294808779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.