Evidence map›Paper›PMID 37431156›Full record

ReviewThe journals of gerontology. Series A, Biological sciences and medical sciences2023

The Health, Aging, and Body Composition (Health ABC) Study-Ground-Breaking Science for 25 Years and Counting.

Anne B Newman, Marjolein Visser, Stephen B Kritchevsky, Eleanor Simonsick, Peggy M Cawthon, Tamara B Harris

Registry-linked trialAbstract readReview
In one paragraph

Review in The journals of gerontology. Series A, Biological sciences and medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06705946 (Effects of Dynamic Stability Training Using Water Inertia Load on Lower Limb Joint Moments, Gait and Balance in Elderly Women), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06705946 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Dynamic Stability Training Using Water Inertia Load on Lower Limb Joint Moments, Gait and Balance in Elderly Women

TypeinterventionalSponsorHyun Ju KimRan2024 to 2025Enrolled24ConditionsBalance and Gait Impairment in Elderly WomenArmsAqua vest group, Weight vest group
3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Observational
  5. Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Indirect estimates of cellular hydration and relative water content and their associations with muscle strength and physical function in older adults: a path analysis from the Pro-Eva study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Article
  13. Associations of Blood Mitochondrial DNA Quality and Quantity with Risk of Kidney Function Decline.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  14. Observational
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. F2-Isoprostanes Are Associated With Increased Fracture Risk in Type 2 Diabetes.The Journal of clinical endocrinology and metabolism · 2025
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anne B NewmanDepartment of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-0106-1150
Marjolein VisserDepartment of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-5136-298X
Stephen B KritchevskyDepartment of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.ORCID 0000-0003-3336-6781
Eleanor SimonsickNational Institute on Aging, Translational Gerontology Branch Biomedical Research Center, Baltimore, Maryland, USA.ORCID 0000-0002-5460-3494
Peggy M CawthonResearch Institute, California Pacific Medical Center, University of California, San Francisco, California, USA.
Tamara B HarrisLaboratory of Epidemiology and Population Sciences, Intramural Research Program NIA, NIH, Bethesda, Maryland, USA.

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Denise Kathryn Houston · 2002 to 2026
$36.4M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
Health, Aging and Body Composition StudyZIAAG007390 · NIA · NATIONAL INSTITUTE ON AGING · PI LAUNER, LENORE J · 2009 to 2024
$4.0M
NIA NIH HHS P30 AG021332NIA NIH HHS P30 AG024827
6 · The paper itself

Abstract

backgroundThe Health, Aging, and Body Composition Study is a longitudinal cohort study that started just over 25 years ago. This ground-breaking study tested specific hypotheses about the importance of weight, body composition, and weight-related health conditions for incident functional limitation in older adults.

methodsNarrative review with analysis of ancillary studies, career awards, publications, and citations.

resultsKey findings of the study demonstrated the importance of body composition as a whole, both fat and lean mass, in the disablement pathway. The quality of the muscle in terms of its strength and its composition was found to be a critical feature in defining sarcopenia. Dietary patterns and especially protein intake, social factors, and cognition were found to be critical elements for functional limitation and disability. The study is highly cited and its assessments have been widely adopted in both observational studies and clinical trials. Its impact continues as a platform for collaboration and career development.

conclusionsThe Health ABC provides a knowledge base for the prevention of disability and promotion of mobility in older adults.

Indexed as

AgingSarcopeniaAgedBody CompositionCohort StudiesHumansLongitudinal StudiesAgingBody compositionEpidemiologySarcopenia

Identifiers

PMID37431156
PMCPMC10613019

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.