Evidence map›Paper›PMID 37430980›Full record

ReviewFoods (Basel, Switzerland)2022

Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19.

Abigail García-Castro, Alma Delia Román-Gutiérrez, Araceli Castañeda-Ovando, Raquel Cariño-Cortés, Otilio Arturo Acevedo-Sandoval, Patricia López-Perea, Fabiola Araceli Guzmán-Ortiz

Open access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Abigail García-CastroÁrea Académica de Química, Universidad Autónoma del Estado de Hidalgo, Carretera Pachuca-Tulancingo, Km 4.5 s/n, Mineral de la Reforma, Hidalgo 42184, Mexico.ORCID 0000-0001-8834-1966
Alma Delia Román-GutiérrezÁrea Académica de Química, Universidad Autónoma del Estado de Hidalgo, Carretera Pachuca-Tulancingo, Km 4.5 s/n, Mineral de la Reforma, Hidalgo 42184, Mexico.ORCID 0000-0003-0927-1061
Araceli Castañeda-OvandoÁrea Académica de Química, Universidad Autónoma del Estado de Hidalgo, Carretera Pachuca-Tulancingo, Km 4.5 s/n, Mineral de la Reforma, Hidalgo 42184, Mexico.ORCID 0000-0003-0759-3198
Raquel Cariño-CortésÁrea Académica de Medicina, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Elíseo Ramírez Ulloa, 400, Doctores, Pachuca de Soto 42090, Mexico.ORCID 0000-0003-4776-3534
Otilio Arturo Acevedo-SandovalÁrea Académica de Química, Universidad Autónoma del Estado de Hidalgo, Carretera Pachuca-Tulancingo, Km 4.5 s/n, Mineral de la Reforma, Hidalgo 42184, Mexico.ORCID 0000-0003-0475-7003
Patricia López-PereaÁrea de Ingeniería Agroindustrial, Universidad Politécnica Francisco I. Madero, Francisco I. Madero, Hidalgo 42660, Mexico.ORCID 0000-0002-3603-788X
Fabiola Araceli Guzmán-OrtizCONACYT, Universidad Autónoma del Estado de Hidalgo, Carretera Pachuca-Tulancingo Km 4.5 s/n, Mineral de la Reforma, Hidalgo 42184, Mexico.ORCID 0000-0003-1333-3624
Universidad Autónoma del Estado de Hidalgo · MXUniversidad Madero · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cereals have phytochemical compounds that can diminish the incidence of chronic diseases such as hypertension. The angiotensin-converting enzyme 2 (ACE2) participates in the modulation of blood pressure and is the principal receptor of the virus SARS-CoV-2. The inhibitors of the angiotensin-converting enzyme (ACE) and the block receptors of angiotensin II regulate the expression of ACE2; thus, they could be useful in the treatment of patients infected with SARS-CoV-2. The inferior peptides from 1 to 3 kDa and the hydrophobic amino acids are the best candidates to inhibit ACE, and these compounds are present in rice, corn, wheat, oats, sorghum, and barley. In addition, the vitamins C and E, phenolic acids, and flavonoids present in cereals show a reduction in the oxidative stress involved in the pathogenesis of hypertension. The influence of ACE on hypertension and COVID-19 has turned into a primary point of control and treatment from the nutritional perspective. The objective of this work was to describe the inhibitory effect of the angiotensin-converting enzyme that the bioactive compounds present in cereals possess in order to lower blood pressure and how their consumption could be associated with reducing the virulence of COVID-19.

Indexed as

cerealsCOVID-19diet therapydrug therapyhypertensionphytochemicals

Identifiers

PMID37430980
PMCPMC9601750
OpenAlexW4306377377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.