Evidence map›Paper›PMID 37430516›Full record

ArticleSensors (Basel, Switzerland)2023

NanoFN10: A High-Contrast Turn-On Fluorescence Nanoprobe for Multiphoton Singlet Oxygen Imaging.

Renzo P Zanocco, Roger Bresolí-Obach, Francisco Nájera, Ezequiel Pérez-Inestrosa, Antonio L Zanocco, Else Lemp, Santi Nonell

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Renzo P ZanoccoDepartamento de Química Orgánica y Fisicoquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago 8330015, Chile.
Roger Bresolí-ObachInstitut Químic de Sarrià, Universitat Ramon Llull, Via Augusta 390, 08017 Barcelona, Spain.
Francisco NájeraDepartamento de Química Orgánica, Universidad de Málaga, Campus Teatinos s/n, 29071 Málaga, Spain.ORCID 0000-0002-1635-5514
Ezequiel Pérez-InestrosaDepartamento de Química Orgánica, Universidad de Málaga, Campus Teatinos s/n, 29071 Málaga, Spain.ORCID 0000-0001-7546-5273
Antonio L ZanoccoDepartamento de Química Orgánica y Fisicoquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago 8330015, Chile.
Else LempDepartamento de Química Orgánica y Fisicoquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago 8330015, Chile.
Santi NonellInstitut Químic de Sarrià, Universitat Ramon Llull, Via Augusta 390, 08017 Barcelona, Spain.ORCID 0000-0002-8900-5291
University of Chile · CLAndalusian Centre for Nanomedicine and Biotechnology · ESInstitut Químic de Sarrià · ES

Funding

Agencia Estatal de Investigación PID2019-104293GB-I00Agencia Estatal de Investigación PID2020-115801RB-C22Agencia Estatal de Investigación RYC2021-032773-IChilean National Commission for Scientific and Technological Research FONDECYT 1150210Departament de Recerca i Universitats de la Generalitat de Catalunya 2021 SGR 01023Institució Catalana de Recerca i Estudis Avançats Ac2232308Ministry of Economy, Industry and Competitiveness CTQ2016-78454-C2-1-R
6 · The paper itself

Abstract

An "off-on" fluorescent nanoprobe for near-infrared multiphoton imaging of singlet oxygen has been developed. The nanoprobe comprises a naphthoxazole fluorescent unit and a singlet-oxygen-sensitive furan derivative attached to the surface of mesoporous silica nanoparticles. In solution, the fluorescence of the nanoprobe increases upon reaction with singlet oxygen both under one- and multiphoton excitation, with fluorescence enhancements up to 180-fold. The nanoprobe can be readily internalized by macrophage cells and is capable of imaging intracellular singlet oxygen under multiphoton excitation.

Indexed as

fluorescent nanoprobemultiphoton excitationsinglet oxygen

Identifiers

PMID37430516
PMCPMC10222627
OpenAlexW4382295524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.