Evidence map›Paper›PMID 37430436›Full record

ArticlePediatric blood & cancer2023

Children's Oncology Group's 2023 blueprint for research: Soft tissue sarcomas.

Sapna Oberoi, Jacquelyn N Crane, Josephine H Haduong, Erin R Rudzinski, Suzanne L Wolden, Roshni Dasgupta, Corinne M Linardic, Aaron R Weiss, Rajkumar Venkatramani, the Children's Oncology Group Soft Tissue Sarcoma Committee

Open access · bronzeAbstract read
In one paragraph

Article in Pediatric blood & cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Sarcomas in Adolescents and Young Adults.Current oncology reports · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
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  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 2 countries.

Sapna OberoiDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0002-6071-0042
Jacquelyn N CraneDepartment of Pediatrics, Stanford University, Stanford, California, USA.
Josephine H HaduongDivision of Oncology, Hyundai Cancer Institute, Children's Hospital Orange County, Orange, California, USA.
Erin R RudzinskiDivision of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-7591-956X
Suzanne L WoldenDepartment of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Roshni DasguptaDivision of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Corinne M LinardicDepartment of Pediatrics, Duke University School of Medicine, Durham, North Carolina, USA.
Aaron R WeissDepartment of Pediatrics, Maine Medical Center, Portland, Maine, USA.
Rajkumar VenkatramaniDivision of Hematology/Oncology, Department of Pediatrics, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
the Children's Oncology Group Soft Tissue Sarcoma Committee
Baylor College of Medicine · USCancerCare Manitoba · CAChildren's Hospital of Orange County · USCincinnati Children's Hospital Medical Center · USDuke University · USMaine Medical Center · USMemorial Sloan Kettering Cancer Center · USSeattle Children's Hospital · USStanford University · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG FOREIGN ACCRUALU10CA098543 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI ADAMSON, PETER C. · 2003 to 2013
$335.5M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
Children's Oncology Group Statistics &Data Center GrantU10CA098413 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI DEVIDAS, MEENAKSHI · 2003 to 2013
$67.5M
COG U24 Funding 2026-2027U24CA196173 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Mignon Lee-Cheun Loh, Nilsa Del Carmen Ramirez Milan · 2015 to 2026
$62.5M
Support for Human Specimen Banking in NCI-Supported Cancer Clinical TrialsU24CA114766 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI RAMIREZ MILAN, NILSA DEL CARMEN · 2005 to 2014
$14.5M
MaineHealth Cancer Care Network (MHCCN) and NCORP Activities across the LifespanUG1CA239771 · NCI · MAINEHEALTH · PI Leslie Bradford, Christine Lu-Emerson · 2019 to 2026
$7.9M
NCI NIH HHS U10 CA098413NCI NIH HHS U10 CA098543NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899NCI NIH HHS U24 CA114766NCI NIH HHS U24 CA196173NCI NIH HHS UG1 CA239771NIH HHS U10CA098413NIH HHS U10CA098543NIH HHS U10CA180886NIH HHS U10CA180899NIH HHS U24CA114766NIH HHS U24CA196173
6 · The paper itself

Abstract

In the United States, approximately 850-900 children and adolescents each year are diagnosed with soft tissue sarcomas (STS). STS are divided into rhabdomyosarcoma (RMS) and non-rhabdomyosarcoma STS (NRSTS). RMS and NRSTS are risk stratified into low-, intermediate-, and high-risk categories, with 5-year survival rates of approximately 90%, 50%-70%, and 20%, respectively. Recent key achievements from the Children's Oncology Group (COG) STS Committee include the identification of new molecular prognostic factors for RMS, development and validation of a novel risk stratification system for NRSTS, successful completion of a collaborative NRSTS clinical trial with adult oncology consortia, and collaborative development of the INternational Soft Tissue SaRcoma ConsorTium (INSTRuCT). Current COG trials for RMS are prospectively evaluating a new risk stratification system that incorporates molecular findings, de-intensification of therapy for a very low-risk subgroup, and augmented therapy approaches for intermediate- and high-risk RMS. Trials for NRSTS exploring novel targets and local control modalities are in development.

Indexed as

RhabdomyosarcomaSarcomaSoft Tissue NeoplasmsAdolescentAdultChildHumansMedical OncologySurvival Ratecancerchildrendesmoid tumornon-rhabdomyosarcoma soft tissue sarcomarhabdomyosarcoma

Identifiers

PMID37430436
PMCPMC10519430
OpenAlexW4383872272

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.