ArticleNature chemistry2023
Experimental quantitation of molecular conditions responsible for flow-induced polymer mechanochemistry.
Article in Nature chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- The mechanochemical activation of a pyrimidine dimer.Chemical science · 2026Article
- Mechanochemical and machine-intelligent design of programmable materials: From molecular interactions to macroscale functionality.Materials today. Bio · 2026Review
- Thermally Bistable Stiff Stilbene Photoswitches and Polymer Applications.Chemical record (New York, N.Y.) · 2026Article
- Polymer microbubbles as universal platform to accelerate polymer mechanochemistry.Nature communications · 2025Article
- Mechanochemistry: Fundamental Principles and Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Biphasic mechanochemistry of single-chain polymerization.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The Role of Torsion on the Force-Coupled Reactivity of a Fluorenyl Naphthopyran Mechanophore.Journal of the American Chemical Society · 2025Article
- Autonomic Self-Healing of Polymers: Mechanisms, Applications, and Challenges.Molecules (Basel, Switzerland) · 2025Review
- Molecularly Shielded, On-Demand, Ultrasound-Cured Polymer Networks.Macromolecules · 2024Article
- Mechanochemical Approaches to Fundamental Studies in Soft-Matter Physics.Angewandte Chemie (International ed. in English) · 2024Review
- Sacrificial Mechanical Bond is as Effective as a Sacrificial Covalent Bond in Increasing Cross-Linked Polymer Toughness.Journal of the American Chemical Society · 2023Article
- Coumarin Dimer Is an Effective Photomechanochemical AND Gate for Small-Molecule Release.Journal of the American Chemical Society · 2023Article
- How polymers dance to the pulses of ultrasound.Nature chemistry · 2023Article
- Allosteric control of olefin isomerization kinetics via remote metal binding and its mechanochemical analysis.Nature communications · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Fragmentation of macromolecular solutes in rapid flows is of considerable fundamental and practical importance. The sequence of molecular events preceding chain fracture is poorly understood, because such events cannot be visualized directly but must be inferred from changes in the bulk composition of the flowing solution. Here we describe how analysis of same-chain competition between fracture of a polystyrene chain and isomerization of a chromophore embedded in its backbone yields detailed characterization of the distribution of molecular geometries of mechanochemically reacting chains in sonicated solutions. In our experiments the overstretched (mechanically loaded) chain segment grew and drifted along the backbone on the same timescale as, and in competition with, the mechanochemical reactions. Consequently, only <30% of the backbone of a fragmenting chain is overstretched, with both the maximum force and the maximum reaction probabilities located away from the chain centre. We argue that quantifying intrachain competition is likely to be mechanistically informative for any flow fast enough to fracture polymer chains.
Identifiers
37430105What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.