Evidence map›Paper›PMID 37430103›Full record

ArticleCommunications medicine2023

Automatic comprehensive radiological reports for clinical acute stroke MRIs.

Chin-Fu Liu, Yi Zhao, Vivek Yedavalli, Richard Leigh, Vitor Falcao, STIR and VISTA Imaging investigators, Michael I Miller, Argye E Hillis, Andreia V Faria

Open access · goldAbstract read
In one paragraph

Article in Communications medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 14 institutions in 7 countries.

Chin-Fu LiuCenter for Imaging Science, Johns Hopkins University, Baltimore, MD, USA.
Yi ZhaoDepartment of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA.ORCID http://orcid.org/0000-0003-4766-5934
Vivek YedavalliDepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Richard LeighDepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-8285-1815
Vitor FalcaoWeiss Memorial Hospital, Chicago, IL, USA.
STIR and VISTA Imaging investigators
Michael I MillerCenter for Imaging Science, Johns Hopkins University, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-4689-3855
Argye E HillisDepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Andreia V FariaDepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. afaria1@jhmi.edu.ORCID http://orcid.org/0000-0002-1673-002X
Johns Hopkins University · USNational Institutes of Health · USHarvard University · USThe Royal Melbourne Hospital · AUUlsan College · KRUniversität Hamburg · DEClinical Research Institute · USHeidelberg University · DEIndiana University School of MedicineSiemens (United States) · USStanford University · USUCLA Health · USUniversity Hospital of Lausanne · CHWeiss Memorial Hospital · US

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FRIDRIKSSON, JULIUS · 2016 to 2025
$25.0M
Neural Basis of Lexical Deficits in Hyperacute StrokeR01DC005375 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI Argye E. Hillis · 2002 to 2026
$11.8M
TRD 4: Platforms for multi-modal and multi-scale imaging dataP41EB031771 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Hanzhang Lu, Peter CM Van Zijl · 2021 to 2026
$9.9M
The Neural Basis of Impaired Affective Prosody in Alzheimer's Disease and Frontotemporal DegenerationR01DC015466 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI HILLIS, ARGYE E. · 2017 to 2021
$3.5M
NIBIB NIH HHS P41 EB031771NIDCD NIH HHS P50 DC014664NIDCD NIH HHS R01 DC005375NIDCD NIH HHS R01 DC015466
6 · The paper itself

Abstract

backgroundAlthough artificial intelligence systems that diagnosis among different conditions from medical images are long term aims, specific goals for automation of human-labor, time-consuming tasks are not only feasible but equally important. Acute conditions that require quantitative metrics, such as acute ischemic strokes, can greatly benefit by the consistency, objectiveness, and accessibility of automated radiological reports.

methodsWe used 1,878 annotated brain MRIs to generate a fully automated system that outputs radiological reports in addition to the infarct volume, 3D digital infarct mask, and the feature vector of anatomical regions affected by the acute infarct. This system is associated to a deep-learning algorithm for segmentation of the ischemic core and to parcellation schemes defining arterial territories and classically-identified anatomical brain structures.

resultsHere we show that the performance of our system to generate radiological reports was comparable to that of an expert evaluator. The weight of the components of the feature vectors that supported the prediction of the reports, as well as the prediction probabilities are outputted, making the pre-trained models behind our system interpretable. The system is publicly available, runs in real time, in local computers, with minimal computational requirements, and it is readily useful for non-expert users. It supports large-scale processing of new and legacy data, enabling clinical and translational research.

conclusionThe generation of reports indicates that our fully automated system is able to extract quantitative, objective, structured, and personalized information from stroke MRIs.

Identifiers

PMID37430103
PMCPMC10333348
OpenAlexW4383816799

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.