Evidence map›Paper›PMID 37430019›Full record

ReviewArchives of microbiology2023

The possible role of Helicobacter pylori in liver diseases.

Mahnaz Mohammadi, Adeleh Attar, Maryam Mohammadbeigi, Amir Peymani, Shahin Bolori, Fatemeh Fardsanei

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Evaluation ofIranian journal of microbiology · 2025
    Article
  3. Article
  4. Article
  5. Beyond the stomach: the association betweenFrontiers in cellular and infection microbiology · 2025
    Review
  6. Review
  7. International journal of biological sciences · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mahnaz MohammadiMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Adeleh AttarMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Maryam MohammadbeigiMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Amir PeymaniMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Shahin BoloriMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Fatemeh FardsaneiMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran. Atefeh_fardsanei@yahoo.com.
Qazvin University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to previous studies, Helicobacter pylori infection is associated with liver disease. In order to better understand the risk of acquiring various liver diseases, we reviewed current knowledge on the impact of H. pylori on the onset, intensification, and progression of various liver diseases caused by the infection of H. pylori. It has been estimated that between 50 and 90% of people worldwide have been infected with H. pylori. The bacterium is mostly responsible for inflamed gastric mucosa, ulcers, and cancers associated with the gastric mucosa. Through the active antioxidant system in H. pylori, the bacteria can neutralize free radicals by synthesizing VacA, a toxin that causes cell damage and apoptosis. Furthermore, there is a possibility that CagA genes may play a role in cancer development. People who have been infected with H. pylori are likely to develop lesions in the skin, the circulation system, and the pancreas. Moreover, transferring blood from the stomach may allow H. pylori to colonize the liver. The bacterium worsened liver function during autoimmune inflammation, toxic injury, chronic HCV infection, chronic HBV infection, and liver cirrhosis. Increasing portal pressure, hyperammonemia, and esophageal varices may be associated with H pylori infection. As a result, it is crucial to diagnose and treat this infection in patients with H. pylori.

Indexed as

Helicobacter InfectionsHelicobacter pyloriHepatitis CLiver DiseasesAntioxidantsHumansAntioxidantsAnd HCVHelicobacter pyloriHPVLiver diseases

Identifiers

PMID37430019
OpenAlexW4383872384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.