Evidence map›Paper›PMID 37429958›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2023

Response to aerosolized calfactant in infants with respiratory distress syndrome; a post-hoc analysis of AERO-02 trial.

Dinushan C Kaluarachchi, Henry A Zapata, Heather L Becker, Michael R Lasarev, Prem Fort, Scott O Guthrie

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Dinushan C KaluarachchiDepartment of Pediatrics, Division of Neonatology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA. kaluarachchi@pediatrics.wisc.edu.ORCID 0000-0001-8334-6282
Henry A ZapataDepartment of Pediatrics, Division of Neonatology, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Heather L BeckerDepartment of Respiratory Therapy, UnityPoint Health Meriter Hospital, Madison, WI, USA.
Michael R LasarevDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.ORCID 0000-0002-1896-2705
Prem FortDepartment of Pediatrics, Division of Neonatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Scott O GuthrieDepartment of Pediatrics, Division of Neonatology, Vanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0000-0001-9703-5266
University of Wisconsin–Madison · USJohns Hopkins University · USMeriter Hospital · USVanderbilt University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aerosolized calfactant decreased the need for intubation in neonates with respiratory distress syndrome (AERO-02 trial).

objectiveTo determine the oxygenation response to aerosolized calfactant among infants born 28 0/7-36 6/7 weeks with RDS in the AERO-02 trial.

methodsTrends in hourly fraction of oxygen (FiO

resultsA total of 353 subjects were included in the study. FiO

conclusionFiO

Indexed as

Biological ProductsRespiratory Distress SyndromeRespiratory Distress Syndrome, NewbornHumansInfantInfant, NewbornOxygenBiological ProductscalfactantOxygen

Identifiers

PMID37429958
OpenAlexW4383814932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.