Evidence map›Paper›PMID 37429937›Full record

ArticleCommunications biology2023

Intermediately synchronised brain states optimise trade-off between subject specificity and predictive capacity.

Leonard Sasse, Daouia I Larabi, Amir Omidvarnia, Kyesam Jung, Felix Hoffstaedter, Gerhard Jocham, Simon B Eickhoff, Kaustubh R Patil

Abstract read
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Variation in high-amplitude events across the human lifespan.Network neuroscience (Cambridge, Mass.) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
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  12. Article
  13. Living on the edge: network neuroscience beyond nodes.Trends in cognitive sciences · 2023
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leonard SasseInstitute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Research Centre Jülich, Jülich, Germany.ORCID 0000-0002-2400-3404
Daouia I LarabiInstitute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Research Centre Jülich, Jülich, Germany.ORCID 0000-0001-7381-6076
Amir OmidvarniaInstitute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Research Centre Jülich, Jülich, Germany.ORCID 0000-0002-4744-8721
Kyesam JungInstitute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Research Centre Jülich, Jülich, Germany.ORCID 0000-0003-3334-5462
Felix HoffstaedterInstitute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Research Centre Jülich, Jülich, Germany.ORCID 0000-0001-7163-3110
Gerhard JochamInstitute for Experimental Psychology, Faculty of Mathematics and Natural Sciences, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Simon B EickhoffInstitute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Research Centre Jülich, Jülich, Germany.
Kaustubh R PatilInstitute of Neuroscience and Medicine, Brain and Behaviour (INM-7), Research Centre Jülich, Jülich, Germany. k.patil@fz-juelich.de.ORCID 0000-0002-0289-5480

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional connectivity (FC) refers to the statistical dependencies between activity of distinct brain areas. To study temporal fluctuations in FC within the duration of a functional magnetic resonance imaging (fMRI) scanning session, researchers have proposed the computation of an edge time series (ETS) and their derivatives. Evidence suggests that FC is driven by a few time points of high-amplitude co-fluctuation (HACF) in the ETS, which may also contribute disproportionately to interindividual differences. However, it remains unclear to what degree different time points actually contribute to brain-behaviour associations. Here, we systematically evaluate this question by assessing the predictive utility of FC estimates at different levels of co-fluctuation using machine learning (ML) approaches. We demonstrate that time points of lower and intermediate co-fluctuation levels provide overall highest subject specificity as well as highest predictive capacity of individual-level phenotypes.

Indexed as

BrainMachine LearningHumansPhenotypeResearch PersonnelTime Factors

Identifiers

PMID37429937
PMCPMC10333234

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.