Evidence map›Paper›PMID 37429842›Full record

ArticleNature communications2023

Real-time environmental surveillance of SARS-CoV-2 aerosols.

Joseph V Puthussery, Dishit P Ghumra, Kevin R McBrearty, Brookelyn M Doherty, Benjamin J Sumlin, Amirhossein Sarabandi, Anushka Garg Mandal, Nishit J Shetty, Woodrow D Gardiner, Jordan P Magrecki and 7 more

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Machine-Learning Microfluidic Minute-Scale Microorganism Metrics Monitoring(M6).Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Joseph V PuthusseryCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.ORCID 0000-0002-0185-1187
Dishit P GhumraCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.ORCID 0000-0003-2480-3927
Kevin R McBreartyDepartment of Neurology, Hope Center for Neurological Disease, Knight Alzheimer's Disease Research Center, Washington University, St. Louis, MO, 63110, USA.
Brookelyn M DohertyDepartment of Neurology, Hope Center for Neurological Disease, Knight Alzheimer's Disease Research Center, Washington University, St. Louis, MO, 63110, USA.
Benjamin J SumlinCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.
Amirhossein SarabandiCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.
Anushka Garg MandalCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.
Nishit J ShettyCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.
Woodrow D GardinerDepartment of Neurology, Hope Center for Neurological Disease, Knight Alzheimer's Disease Research Center, Washington University, St. Louis, MO, 63110, USA.
Jordan P MagreckiDepartment of Neurology, Hope Center for Neurological Disease, Knight Alzheimer's Disease Research Center, Washington University, St. Louis, MO, 63110, USA.
David L BrodyNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Thomas J EsparzaNational Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Traci L BrickerDepartment of Medicine, Washington University, St. Louis, MO, 63110, USA.
Adrianus C M BoonDepartment of Medicine, Washington University, St. Louis, MO, 63110, USA.ORCID 0000-0002-4700-8224
Carla M YuedeDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110, USA. yuedec@wustl.edu.ORCID 0000-0001-6362-4767
John R CirritoDepartment of Neurology, Hope Center for Neurological Disease, Knight Alzheimer's Disease Research Center, Washington University, St. Louis, MO, 63110, USA. cirritoj@wustl.edu.
Rajan K ChakrabartyCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA. chakrabarty@wustl.edu.ORCID 0000-0001-5753-9937

Funding

Development of Brain MRI Contrast AgentsZIANS003170 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI KORETSKY, ALAN · 2019 to 2024
$7.7M
Nanobody-Based Electrochemical Biosensor for Real-Time Detection of Aerosolized SARS-CoV2U01AA029331 · NIAAA · WASHINGTON UNIVERSITY · PI CIRRITO, JOHN R · 2021 to 2022
$1.4M
NIAAA NIH HHS U01 AA029331
6 · The paper itself

Abstract

Real-time surveillance of airborne SARS-CoV-2 virus is a technological gap that has eluded the scientific community since the beginning of the COVID-19 pandemic. Offline air sampling techniques for SARS-CoV-2 detection suffer from longer turnaround times and require skilled labor. Here, we present a proof-of-concept pathogen Air Quality (pAQ) monitor for real-time (5 min time resolution) direct detection of SARS-CoV-2 aerosols. The system synergistically integrates a high flow (~1000 lpm) wet cyclone air sampler and a nanobody-based ultrasensitive micro-immunoelectrode biosensor. The wet cyclone showed comparable or better virus sampling performance than commercially available samplers. Laboratory experiments demonstrate a device sensitivity of 77-83% and a limit of detection of 7-35 viral RNA copies/m

Indexed as

COVID-19SARS-CoV-2Environmental MonitoringHumansPandemicsRespiratory Aerosols and Droplets

Identifiers

PMID37429842
PMCPMC10333287

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.