SynthesisRMD open2023
Fibromyalgia and mortality: a systematic review and meta-analysis.
Synthesis in RMD open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Global mortality of glaucoma: a systematic review and meta-analysis of prospective studies.International ophthalmology · 2026Pooled it
- Pooled it
- Are adults with chronic pain more likely to develop hypertension than adults without chronic pain? A systematic review and meta-analysis.British journal of anaesthesia · 2025Pooled it
- Mood states and well-being of spouses of fibromyalgia patients: a systematic review and meta-analysis.Frontiers in psychology · 2024Pooled it
- The impact of rumination on fibromyalgia pain after physical activity: an experimental study.Scientific reports · 2023Trial
- Centralized Pain Diagnoses in Older Adults With and Without Cancer.Journal of pain & palliative care pharmacotherapy · 2026Article
- [Chronic Pain and the Redistribution of Epistemic Power: From Technological Reductionism to Clinical Generalism].Atencion primaria · 2026Article
- A systematic scoping review and conceptual analysis of new-onset fibromyalgia manifestations after non-hospitalized COVID-19: empirics, definitions, methodologies, pathophysiology, mapping of literature, and knowledge gaps.Journal of translational medicine · 2026Article
- Fibromyalgia: Neuropsychological and Clinical Correlates in Suicidal Behavior Based on Ideation-to-Action Models-A Critical Review.Behavioral sciences (Basel, Switzerland) · 2026Review
- Development of a Novel 11-Gene Signature Related to Immune Subtypes for FibromyalgiaEndocrine, metabolic & immune disorders drug targets · 2026Article
- Article
- Exploring Pain on Social Media: Observational Study on Perceptions and Discussions of Chronic Pain Conditions.JMIR infodemiology · 2025Observational
- Effect of Physical Activity on Chronic Widespread Pain: Insights From Meta-Analysis and Two-Sample Mendelian Randomization.Journal of pain research · 2025Article
- Increased Rates of Infectious Diseases in Fibromyalgia Patients: A Population-Based Case-Control Study.Biomedicines · 2024Article
- Article
- Article
- Inflammation, Autoimmunity, and Infection in Fibromyalgia: A Narrative Review.International journal of molecular sciences · 2024Review
- Usefulness of a Multicomponent Group Intervention Program for Fibromyalgia Patients in Primary Care: A Qualitative Study of Health Professionals.Healthcare (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo conduct a systematic review of the literature on the association between fibromyalgia and mortality and to pool the results in a meta-analysis.
methodsThe authors searched the PubMed, Scopus, and Web of Science databases using the key words 'fibromyalgia' and 'mortality' to identify studies that addressed an association between fibromyalgia and mortality. Original papers that assessed associations between fibromyalgia and mortality (all or specific causes) and provided an effect measure (hazard ratio (HR), standardised mortality ratio (SMR), odds ratio (OR)) quantifying the relationship between fibromyalgia and mortality were included in the systematic review. Of 557 papers that were initially identified using the search words, 8 papers were considered eligible for the systematic review and meta-analysis. We used a Newcastle-Ottawa scale to assess the risk of bias in the studies.
resultsThe total fibromyalgia group included 188 751 patients. An increased HR was found for all-cause mortality (HR 1.27, 95% CI 1.04 to 1.51), but not for the subgroup diagnosed by the 1990 criteria. There was a borderline increased SMR for accidents (SMR 1.95, 95% CI 0.97 to 3.92), an increased risk for mortality from infections (SMR 1.66, 95% CI 1.15 to 2.38), and suicide (SMR 3.37, 95% CI 1.52 to 7.50), and a decreased mortality rate for cancer (SMR 0.82, 95% CI 0.69 to 0.97). The studies showed significant heterogeneity.
conclusionsThese potential associations indicate that fibromyalgia should be taken seriously, with a special focus on screening for suicidal ideation, accident prevention, and the prevention and treatment of infections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.