Evidence map›Paper›PMID 37429697›Full record

ArticleBMJ global health2023

Cost-effectiveness of measles and rubella elimination in low-income and middle-income countries.

Ann Levin, Colleen Burgess, Stephanie Shendale, Winthrop Morgan, Raymond Cw Hutubessy, Measles–rubella Eradication Modelling Group, Mark Jit, Measles-rubella Eradication Modelling Group

Open access · goldAbstract read
In one paragraph

Article in BMJ global health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Ann LevinLevin & Morgan LLC, Bethesda, Maryland, USA ann@levinmorgan.com.
Colleen BurgessSelf-employed, Phoenix, Arizona, USA.
Stephanie ShendaleWorld Health Organization, Geneva, Switzerland.
Winthrop MorganLevin & Morgan LLC, Bethesda, Maryland, USA.
Raymond Cw HutubessyWorld Health Organization, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-9286-5065
Measles–rubella Eradication Modelling Group
Mark JitFaculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.
Measles-rubella Eradication Modelling Group
London School of Hygiene & Tropical Medicine · GBMorgan, Lewis & Bockius (United States) · USWorld Health Organization · CHPhoenix (United States) · US

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundSince 2000, the incidence of measles and rubella has declined as measles-rubella (MR) vaccine coverage increased due to intensified routine immunisation (RI) and supplementary immunisation activities (SIAs). The World Health Assembly commissioned a feasibility assessment of eliminating measles and rubella. The objective of this paper is to present the findings of cost-effectiveness analysis (CEA) of ramping up MR vaccination with a goal of eliminating transmission in every country.

methodsWe used projections of impact of routine and SIAs during 2018-2047 for four scenarios of ramping up MR vaccination. These were combined with economic parameters to estimate costs and disability-adjusted life years averted under each scenario. Data from the literature were used for estimating the cost of increasing routine coverage, timing of SIAs and introduction of rubella vaccine in countries.

resultsThe CEA showed that all three scenarios with ramping up coverage above the current trend were more cost-effective in most countries than the 2018 trend for both measles and rubella. When the measles and rubella scenarios were compared with each other, the most cost-effective scenario was likely to be the most accelerated one. Even though this scenario is costlier, it averts more cases and deaths and substantially reduces the cost of treatment.

conclusionsThe Intensified Investment scenario is likely the most cost-effective of the vaccination scenarios evaluated for reaching both measles and rubella disease elimination. Some data gaps on costs of increasing coverage were identified and future efforts should focus on filling these gaps.

Indexed as

MeaslesRubellaCost-Benefit AnalysisDeveloping CountriesHumansPovertyhealth economicsimmunisationmeasles

Identifiers

PMID37429697
PMCPMC10335502
OpenAlexW4383872671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.