Evidence map›Paper›PMID 37429320›Full record

Observational studyAmerican journal of perinatology2024

Urinary Tract Infection Epidemiology in NICUs in the United States.

Ryan Kilpatrick, Angelique E Boutzoukas, Elizabeth Chan, Valerie Girgis, Vincent Kinduelo, Sarah Ama Kwabia, Jenny Yan, Reese H Clark, Kanecia O Zimmerman, Rachel G Greenberg

Open access · greenAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in American journal of perinatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Urinary tract infection in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  2. Review
  3. Review
  4. Epidemiology of bacterial and fungal infections among level IV neonatal units in North America.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ryan KilpatrickDepartment of Pediatrics, Duke University Medical Center, Durham, North Carolina.ORCID 0000-0003-1059-2401
Angelique E BoutzoukasDepartment of Pediatrics, Duke University Medical Center, Durham, North Carolina.
Elizabeth ChanDepartment of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina.ORCID 0000-0002-4953-093X
Valerie GirgisDepartment of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina.
Vincent KindueloDepartment of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina.
Sarah Ama KwabiaDepartment of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina.
Jenny YanDepartment of Pediatrics, Duke Clinical Research Institute, Durham, North Carolina.
Reese H ClarkCenter for Research, Education, Quality, and Safety, Pediatrix Medical Group, Inc, Sunrise, Florida.ORCID 0000-0002-7363-4640
Kanecia O ZimmermanDepartment of Pediatrics, Duke University Medical Center, Durham, North Carolina.
Rachel G GreenbergDepartment of Pediatrics, Duke University Medical Center, Durham, North Carolina.ORCID 0000-0003-4156-8543
Clinical Research Institute · US

Funding

NIH Summer Research Experience Programs (R25)R25HD076475 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2013 to 2023
$1.1M
NIAAA NIH HHS HHSN275201000003CNICHD NIH HHS HHSN275201000003INICHD NIH HHS R25 HD076475
6 · The paper itself

Abstract

objectiveOur objective was to characterize the incidence, associated clinical factors, timing of infection, microbiology, and incidence of concordant blood culture of urinary tract infections (UTIs) in very low birth weight (VLBW <1,500g) infants. STUDY

designMulticenter observational cohort study of VLBW infants with gestational age (GA) ≤32 weeks, still hospitalized on postnatal day 7, and discharged 2010 to 2018 from Pediatrix Medical Group neonatal intensive care units. Demographic and clinical characteristics of infants with and without UTI were compared. Multivariable logistic regression evaluated adjusted odds of UTI diagnosis.

resultsOf 86,492 included infants, 5,988 (7%) had a UTI. The most common pathogen was

conclusionUTI is a common cause of infection in VLBW infants, especially among the smallest, most premature, male infants, and those with a longer duration of hospitalization. Neonatal clinicians should consider obtaining urine culture in the setting of late-onset sepsis evaluations in VLBW infants. KEY POINTS: · UTI is a common cause of LOS in VLBW infants.. · The most common pathogens are Enterococcus spp. and E. coli.. · UTI risk varies among different VLBW infant populations.. · Next steps should include evaluation of preventative measures..

Indexed as

Infant, Very Low Birth WeightIntensive Care Units, NeonatalUrinary Tract InfectionsEnterococcusEscherichia coliFemaleGestational AgeHumansIncidenceInfant, NewbornInfant, PrematureKlebsiellaLength of StayLogistic ModelsMaleRisk Factors

Identifiers

PMID37429320
PMCPMC11326515
OpenAlexW4383746110

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.