Trial reportPsychiatry research2023
Effects of resistance exercise training on depressive symptoms among young adults: A randomized controlled trial.
Trial report in Psychiatry research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06775548 (Effects of Exercises and Vitamins on Oxidative Stress & Inflammatory Markers Among Patients with Depression), which is not on this map. Cited by 27 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Exercises and Vitamins on Oxidative Stress & Inflammatory Markers Among Patients with Depression
Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- The influence of outdoor physical activity on the physical and mental health of college students: a systematic review.Frontiers in psychology · 2026Pooled it
- The Effects of Aerobic and Resistance Exercise on Depression and Anxiety: Systematic Review With Meta-Analysis.International journal of mental health nursing · 2025Pooled it
- A META analysis and systematic review of the effects of exercise interventions on middle-aged and elderly patients with depression.PloS one · 2025Pooled it
- Resistance training for depression: a systematic review and meta-analysis of randomized controlled trials.Frontiers in psychology · 2025Pooled it
- Optimal dose of resistance training to improve handgrip strength in older adults with sarcopenia: a systematic review and Bayesian model-based network meta-analysis.Frontiers in physiology · 2025Pooled it
- Trial
- The effects of exercise on generalized anxiety symptoms in adults: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2026Article
- From Nature to Strength: A Proof-of-Concept Study Integrating a Nature-Based Intervention with Virtually Supported Resistance Training in Young Men.Healthcare (Basel, Switzerland) · 2026Article
- Mechanisms of exercise against anxiety disorder: A review of the research progress.Sports medicine and health science · 2026Review
- Correlation of physical activity with positive and negative affect and frontal lateralization in college students with depressive symptoms.Scientific reports · 2026Article
- Physical activity and depressive symptoms in young adults: a moderated mediation model of neighborhood trust and growth mindset.Frontiers in public health · 2026Article
- Can exercise truly alleviate mild-to-moderate and subthreshold depression? Evidence from randomized controlled trials.Frontiers in psychology · 2026Review
- Comparative Efficacy of Exercise Interventions for Anxiety Disorders: A Bayesian Network Meta-Analysis.Psychology research and behavior management · 2026Review
- The effects of cluster-set resistance training on mental health and sleep quality in sedentary young women: protocol for a randomized controlled trial.Frontiers in psychology · 2026Article
- Kynurenine Pathway Metabolites as Mediators of Exercise-Induced Mood Enhancement, Fatigue Resistance, and Neuroprotection.International journal of molecular sciences · 2025Review
- Anhedonia and PTSD symptom severity profiles differentially influence physical activity volume in trauma-exposed adults.European journal of psychotraumatology · 2025Article
- Childhood insulin resistance and neural stem cell dysfunction in psychiatric disorders: Role ofWorld journal of stem cells · 2025Review
- Exploring exercise, emotional eating, and body dissatisfaction in depression risk: Using structural equation modeling.PloS one · 2025Article
- Efficacy effects of fecal microbiota transplantation on depressive symptoms: a meta-analysis based on randomized controlled trials.Frontiers in psychiatry · 2025Review
- Leisure time exercise and depressive symptoms in sedentary workers: exploring the effects of exercise volume and social context.Frontiers in psychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Evidence supports the antidepressant effects of resistance exercise training (RET); however, findings among young adults at-risk for elevated depressive symptoms are limited. This randomized controlled trial examined the effects of eight weeks of ecologically-valid, guidelines-based RET, compared to a wait-list control, on depressive symptoms among 55 young adults (26±5y; 36 female) with and without subclinical, or analogue, Generalized Anxiety Disorder (AGAD; Psychiatric Diagnostic Screening Questionnaire GAD subscale ≥6 and Penn State Worry Questionnaire ≥45) and Major Depressive Disorder (AMDD). Following a three-week familiarization period, participants completed one-on-one, twice-weekly RET sessions. The 16-item, self-reported Quick Inventory of Depressive Symptomatology (QIDS) assessed depressive symptoms. RM-ANCOVAs examined between-group differences, and significant interactions were decomposed with simple effects analysis. Hedges' d effect sizes (95%CI) quantified the magnitude of differences in change between groups across time. Stratified analyses were conducted among subsamples with AMDD and AGAD. There were no baseline depressive symptom differences between groups. Attendance was 83%, and compliance was 80%. RET induced statistically significant, clinically-meaningful, large-magnitude reductions in depressive symptoms from baseline to week eight in the total (d = 1.01; [95%CI: 0.44-1.57]), AMDD (d = 1.71; [95%CI: 0.96-2.46]), and AGAD (d = 1.39; [95%CI: 0.55-2.24]) samples. These findings support guidelines-based RET as a promising treatment for mild depression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.