SynthesisJournal of medical Internet research2023
Telemedicine-Based Management of Oral Anticoagulation Therapy: Systematic Review and Meta-analysis.
Synthesis in Journal of medical Internet research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- The Effectiveness of Digital Animation-Based Multistage Education for Patients With Atrial Fibrillation Catheter Ablation: Randomized Clinical Trial.Journal of medical Internet research · 2025Trial
- The Effectiveness of Digital Therapeutics Intervention in Oral Anticoagulation Management: A Systematic Review and Meta-analysis.Mayo Clinic proceedings. Digital health · 2026Article
- PICO-based assessment and categorization of evidence for digital health interventions: an inductive framework development.Frontiers in digital health · 2026Review
- An Overview of Reviews on Telemedicine and Telehealth in Dementia Care: Mixed Methods Synthesis.JMIR mental health · 2025Review
- Remote Monitoring Model Based on Artificial Intelligence to Optimize DOAC Therapy: A Working Hypothesis for Safer Anticoagulation.Medicina (Kaunas, Lithuania) · 2025Article
- Shaping the Future of DHT Assessment: Insights on Industry Challenges, Developer Needs, and a Harmonized, European HTA Framework.Journal of market access & health policy · 2025Article
- Enhancing clinical service design for multimorbidity management: A comprehensive approach to joined-up care for diabetes, chronic kidney disease, and heart failure.Diabetic medicine : a journal of the British Diabetic Association · 2025Review
- Oral Anticoagulation with VKAs: Quality Above All!Arquivos brasileiros de cardiologia · 2025Article
- Comparing tele-pharmacy and standard clinic follow-up for newly initiated warfarin anticoagulation therapy: A retrospective study.Saudi medical journal · 2024Article
- Smart approach for international normalized ratio monitoring: Pakistan's perspective.Annals of medicine and surgery (2012) · 2024Article
- Management of Venous and Arterial Thrombosis.Journal of clinical medicine · 2024Article
- Implementing Telemedicine in Clinical Practice in the First Digital Hematology Unit: Feasibility Study.JMIR formative research · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 4 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOral anticoagulation is the cornerstone treatment of several diseases. Its management is often challenging, and different telemedicine strategies have been implemented to support it.
objectiveThe aim of the study is to systematically review the evidence on the impact of telemedicine-based oral anticoagulation management compared to usual care on thromboembolic and bleeding events.
methodsRandomized controlled trials were searched in 5 databases from inception to September 2021. Two independent reviewers performed study selection and data extraction. Total thromboembolic events, major bleeding, mortality, and time in therapeutic range were assessed. Results were pooled using random effect models.
resultsIn total, 25 randomized controlled trials were included (n=25,746 patients) and classified as moderate to high risk of bias by the Cochrane tool. Telemedicine resulted in lower rates of thromboembolic events, though not statistically significant (n=13 studies, relative risk [RR] 0.75, 95% CI 0.53-1.07; I
conclusionsTelemedicine-based oral anticoagulation management resulted in similar rates of major bleeding and mortality, a trend for fewer thromboembolic events, and better anticoagulation quality compared to standard care. Given the potential benefits of telemedicine-based care, such as greater access to remote populations or people with ambulatory restrictions, these findings may encourage further implementation of eHealth strategies for anticoagulation management, particularly as part of multifaceted interventions for integrated care of chronic diseases. Meanwhile, researchers should develop higher-quality evidence focusing on hard clinical outcomes, cost-effectiveness, and quality of life.
trial registrationPROSPERO International Prospective Register of Systematic Reviews CRD42020159208; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=159208.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.