Evidence map›Paper›PMID 37428448›Full record

SynthesisThe journal of spinal cord medicine2024

The effect of neuropathic pain treatments on pain interference following spinal cord injury: A systematic review.

David J Allison, Jessica Ahrens, Magdalena Mirkowski, Swati Mehta, Eldon Loh

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in The journal of spinal cord medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

David J AllisonParkwood Institute, Lawson Health Research Institute, London, Canada.ORCID 0000-0003-3602-236X
Jessica AhrensParkwood Institute, Lawson Health Research Institute, London, Canada.
Magdalena MirkowskiParkwood Institute, Lawson Health Research Institute, London, Canada.
Swati MehtaParkwood Institute, Lawson Health Research Institute, London, Canada.
Eldon LohParkwood Institute, Lawson Health Research Institute, London, Canada.
Lawson Health Research Institute · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextNeuropathic pain is a common and debilitating condition following SCI. While treatments for neuropathic pain intensity have been reviewed, the impact on pain interference has not been summarized.

objectiveTo systematically review the effect of neuropathic pain interventions on pain interference in individuals with spinal cord injury.

methodsThis systematic review included randomized controlled trials and quasi-experimental (non-randomized) studies which assessed the impact of an intervention on pain interference in individuals with spinal cord injury and neuropathic pain. Articles were identified by searching MEDLINE (1996 to April 11, 2022), EMBASE (1996 to April 11, 2022), PsycInfo (1987 to April, week 2, 2022). Studies were assessed for methodologic quality using a modified GRADE approach and were given quality of evidence (QOE) scores on a 4-point scale ranging from very low to high.

resultsTwenty studies met the inclusion criteria. These studies fell into the following categories: anticonvulsants (

conclusionWhen considering studies of moderate to high quality, pregabalin, gabapentin, intrathecal baclofen, transcranial direct current stimulation, and transcutaneous electrical nerve stimulation (in 1 of 2 studies) were shown to have beneficial effects on pain interference. However, due to the low number of high-quality studies further research is required to confirm the efficacy of these interventions prior to recommending their use to reduce pain interference.

Indexed as

NeuralgiaSpinal Cord InjuriesAnalgesicsHumansPain ManagementAnalgesicsNeuropathic painPain interferenceSpinal cord injury

Identifiers

PMID37428448
PMCPMC11218591
OpenAlexW4383711360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.