Evidence map›Paper›PMID 37428435›Full record

ReviewCurrent osteoporosis reports2023

Recommendations for High-resolution Peripheral Quantitative Computed Tomography Assessment of Bone Density, Microarchitecture, and Strength in Pediatric Populations.

L Gabel, K Kent, S Hosseinitabatabaei, A J Burghardt, M B Leonard, F Rauch, B M Willie

Open access · hybridAbstract readReview
In one paragraph

Review in Current osteoporosis reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Lonafarnib clinical trials demonstrate uncoupling of the muscle-bone unit in Hutchinson-Gilford Progeria Syndrome.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Article
  8. Bone microstructural and strength changes over 1 year in children with osteogenesis imperfecta are comparable to age- and sex-matched healthy controls.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Article
  9. Fifteen-minute consultation: Modern diagnostic approach to the child with recurrent fractures.Archives of disease in childhood. Education and practice edition · 2026
    Article
  10. Article
  11. Article
  12. The association between physical activity during growth and bone microarchitecture at peak bone mass.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Article
  13. Article
  14. Article
  15. Ambulatory children with spastic cerebral palsy have smaller bone area and deficits in trabecular microarchitecture.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

L GabelHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, 2500 University Dr NW, Calgary, AB, T2N 1N4, Canada. leigh.gabel@ucalgary.ca.ORCID 0000-0002-7429-2750
K KentDepartment of Pediatrics, Stanford School of Medicine, Stanford, CA, USA.
S HosseinitabatabaeiResearch Centre, Shriners Hospital for Children-Canada, Montreal, Canada.ORCID 0000-0002-5638-976X
A J BurghardtDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-6343-4944
M B LeonardDepartment of Pediatrics, Stanford School of Medicine, Stanford, CA, USA.
F RauchResearch Centre, Shriners Hospital for Children-Canada, Montreal, Canada.ORCID 0000-0002-6261-0360
B M WillieResearch Centre, Shriners Hospital for Children-Canada, Montreal, Canada.ORCID 0000-0003-2907-3580
Shriners Hospitals for Children - Canada · CAStanford Medicine · USUniversity of Calgary · CAUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to summarize current approaches and provide recommendations for imaging bone in pediatric populations using high-resolution peripheral quantitative computed tomography (HR-pQCT). RECENT

findingsImaging the growing skeleton is challenging and HR-pQCT protocols are not standardized across centers. Adopting a single-imaging protocol for all studies is unrealistic; thus, we present three established protocols for HR-pQCT imaging in children and adolescents and share advantages and disadvantages of each. Limiting protocol variation will enhance the uniformity of results and increase our ability to compare study results between different research groups. We outline special cases along with tips and tricks for acquiring and processing scans to minimize motion artifacts and account for growing bone. The recommendations in this review are intended to help researchers perform HR-pQCT imaging in pediatric populations and extend our collective knowledge of bone structure, architecture, and strength during the growing years.

Indexed as

Bone DensityTomography, X-Ray ComputedAdolescentBone and BonesChildHumansRadiusBoneHR-pQCTImagingPediatric

Identifiers

PMID37428435
PMCPMC10543577
OpenAlexW4383711111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.