Evidence map›Paper›PMID 37428299›Full record

Observational studyInternational ophthalmology2023

The large Hellenic Study of Uveitis: epidemiology, etiologic factors and classification.

Dimitrios Kalogeropoulos, Ioannis Asproudis, Maria Stefaniotou, Marilita M Moschos, Vassilios P Kozobolis, Paraskevi V Voulgari, Andreas Katsanos, Constantina Gartzonika, Chris Kalogeropoulos

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  8. Article
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  11. Review
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  13. Pattern of uveitis in a referral ophthalmology center in Northeastern Thailand.Journal of ophthalmic inflammation and infection · 2024
    Article
  14. Treatment of uveitis and scleritis patients in Malaysia.International journal of ophthalmology · 2024
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Dimitrios KalogeropoulosDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, University Campus, 451 10, Ioannina, Greece. dkalog1990@gmail.com.ORCID http://orcid.org/0000-0001-6404-5409
Ioannis AsproudisDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, University Campus, 451 10, Ioannina, Greece.
Maria StefaniotouDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, University Campus, 451 10, Ioannina, Greece.
Marilita M Moschos1st Department of Ophthalmology, General Hospital of Athens G. Gennimatas, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Vassilios P KozobolisDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Patras, Patras, Greece.
Paraskevi V VoulgariDepartment of Rheumatology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Andreas KatsanosDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, University Campus, 451 10, Ioannina, Greece.
Constantina GartzonikaLaboratory of Microbiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Chris KalogeropoulosDepartment of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, University Campus, 451 10, Ioannina, Greece.
University of Ioannina · GRNational and Kapodistrian University of Athens · GRUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyse the demography, etiology, and classification of uveitis at a tertiary academic referral center.

methodsAn observational study was conducted on the archives of uveitic patients at the Ocular Inflammation Service of the Department of Ophthalmology at the University Hospital of Ioannina (Greece) from 1991 to 2020. This study aimed to investigate the epidemiological profile of patients, including their demographics and the main etiologic factors of uveitis.

resultsOut of 6191 cases with uveitis, 1925 were infectious, 4125 were non-infectious, and an overall of 141 masquerade syndromes were recorded. Among these cases, 5950 patients were adults, with a slight female predominance, while 241 were children (< 18 years old). Interestingly, 24.2% of cases (1500 patients) were associated with 4 specific microorganisms. Herpetic uveitis (HSV-1 and VZV/HZV) was the most common cause of infectious uveitis (14.87%), followed by toxoplasmosis (6.6%) and tuberculosis (2.74%). In 49.2% of non-infectious uveitis cases, no systematic correlation was found. The most frequent causes of non-infectious uveitis included sarcoidosis, white dot syndromes, ankylosing spondylitis, lens-induced uveitis, Adamantiades-Behçet disease, and idiopathic juvenile arthritis. Infectious uveitis was more common in the rural population, whereas non-infectious uveitis was more frequently recorded in the urban population

conclusionsAlthough our study was conducted on a predominantly white Caucasian population, it also reflects the effect of increasing immigration, improvements of diagnostic techniques, changes in referral patterns, and various actual changes in disease incidence.

Indexed as

Behcet SyndromeUveitisAdolescentAdultChildFemaleHumansMaleMorbidityReferral and ConsultationRetrospective StudiesTertiary Care CentersDemographyEpidemiologyInfectiousNon-infectiousUveitis

Identifiers

PMID37428299
PMCPMC10504180
OpenAlexW4383711061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.