Evidence map›Paper›PMID 37428017›Full record

ArticleeLife2023

From actin waves to mechanism and back: How theory aids biological understanding.

Carsten Beta, Leah Edelstein-Keshet, Nir Gov, Arik Yochelis

Abstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Single-cell chiral symmetry breaking under confinement.bioRxiv : the preprint server for biology · 2026
    Article
  6. Actin network heterogeneity tunes activator-inhibitor dynamics at the cell cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Signaling and actin waves at a glance.Journal of cell science · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Morphogenic Modeling of Corrosion Reveals Complex Effects of Intermetallic Particles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Patterning of the cell cortex by Rho GTPases.Nature reviews. Molecular cell biology · 2024
    Review
  17. Article
  18. Methods and computational tools to study eukaryotic cell migrationFrontiers in cell and developmental biology · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carsten BetaInstitute of Physics and Astronomy, University of Potsdam, Potsdam, Germany.ORCID 0000-0002-0100-1043
Leah Edelstein-KeshetDepartment of Mathematics, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0002-2233-690X
Nir GovDepartment of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0001-7774-1139
Arik YochelisSwiss Institute for Dryland Environmental and Energy Research, Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev, Sede Boqer Campus, Midreshet Ben-Gurion, Israel.ORCID 0000-0002-1516-0766

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Actin dynamics in cell motility, division, and phagocytosis is regulated by complex factors with multiple feedback loops, often leading to emergent dynamic patterns in the form of propagating waves of actin polymerization activity that are poorly understood. Many in the actin wave community have attempted to discern the underlying mechanisms using experiments and/or mathematical models and theory. Here, we survey methods and hypotheses for actin waves based on signaling networks, mechano-chemical effects, and transport characteristics, with examples drawn from

Indexed as

ActinsDictyosteliumActin CytoskeletonCell MovementHumansModels, BiologicalPhagocytosisSignal TransductionActinsactinbifurcationcell biologychemical signalingcomputational biologyeukaryotic cellspattern formationsystems biologysystems modelingwaves

Identifiers

PMID37428017
PMCPMC10332813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.