ArticleFrontiers in public health2023
Association between bone mineral density and cardiovascular disease in older adults.
Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Determinants and associated factors for hallux valgus: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Association Between Hemoglobin Glycation Index and Prevalence of Cardiovascular Disease in Middle-Aged and Older Adults With Hip Fracture: Findings From CHARLS and NHANES.Clinical cardiology · 2026Article
- Hybrid deep learning time-to-event modeling of major adverse cardiovascular events using coronary artery calcium score scans.European journal of radiology artificial intelligence · 2026Article
- Bone as a Biomarker of Ageing and Senescence: Connecting Musculoskeletal Health to Longevity via Diet, Nutrition and Exercise.Biology · 2026Review
- Osteoporosis and cardiac remodeling in middle-aged and older adults: a cross-sectional study.Scientific reports · 2026Article
- Segmental Bioimpedance Phase Angles for Frailty Detection in Hospitalized Older Adults with Cardiovascular Disease: A Cross-Sectional Observational Study.Healthcare (Basel, Switzerland) · 2025Article
- The association of bone mineral density with cardiovascular disease and mortality among individuals with/without type 2 diabetes: a population-based retrospective cohort.Diabetology & metabolic syndrome · 2025Article
- Associations between cardiac adipose tissue and abdominal visceral fat and muscle based on computed tomography area and density.Scientific reports · 2025Article
- Association Between Bone Ultrasonometry and Cardiovascular Morbimortality: A Systematic Review and Meta-analysis.Journal of the Endocrine Society · 2025Review
- Association Between Serum Apolipoprotein B and Bone Mineral Density and the Effects of Cardiovascular Disease Mediation: Results From the NHANES 2011-2016 and a Mendelian Randomization Study.Reviews in cardiovascular medicine · 2025Article
- The relationship between geriatric nutritional risk index and cardiovascular disease and all-cause mortality in patients with osteoporosis and osteopenia.Journal of geriatric cardiology : JGC · 2025Article
- A cross-sectional study comparing machine learning and logistic regression techniques for predicting osteoporosis in a group at high risk of cardiovascular disease among old adults.BMC geriatrics · 2025Article
- Association between bone mineral density and vascular health in rheumatoid arthritis.Singapore medical journal · 2025Article
- Risk of adverse cardiovascular events following spinal cord injury in patients with osteoporosis: Real-world evidence.American journal of preventive cardiology · 2025Article
- Association between life's essential 8 and bone mineral density among adults aged 20-59 years.Scientific reports · 2025Article
- Improving Sleep Quality and Well-Being in Institutionalized Older Adults: The Potential of NESA Non-Invasive Neuromodulation Treatment.Geriatrics (Basel, Switzerland) · 2025Article
- Association of skin-advanced glycation end products, IMT complex, and bone mineral density in patients with type 1 diabetes.Frontiers in endocrinology · 2025Article
- Bone health, cardiovascular disease, and imaging outcomes in UK Biobank: a causal analysis.JBMR plus · 2024Article
- The multi-faceted nature of age-associated osteoporosis.Bone reports · 2024Review
- Osteoporosis and coronary heart disease: a bi-directional Mendelian randomization study.Frontiers in endocrinology · 2024Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aims: Cardiovascular disease and osteoporosis are common diseases in older adults with high morbidity. The study on the interaction between the two in pathogenic mechanisms has been paid much attention by the majority of researchers. This study aimed to explore the relationship between bone mineral density and cardiovascular disease in older adults. Methods: The primary data was downloaded from the National Health and Nutrition Examination Survey database of the United States. Multivariate logistic regression model, generalized additive model, and smooth curve fitting were used to explore the relationship between bone mineral density and cardiovascular events risk. When a curve relationship was found, a two-piecewise linear model was used to calculate the inflection point. In addition, subgroup analysis was also performed. Results: A total of 2097 subjects were included in this study. After adjusting for potential confounders, no significant association was found between lumbar bone mineral density and cardiovascular disease, while femur bone mineral density had a non-linear relationship with cardiovascular disease, with an inflection point of 0.741 gm/cm Conclusion: Our results indicated that bone mineral density was closely associated with the prevalence of cardiovascular disease in older adults over 60 years old, especially the femur bone mineral density was negatively non-linear associated with cardiovascular disease risk, with an inflection point of 0.741 gm/cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.