ReviewFrontiers in neuroanatomy2023
Deconvoluting human Brodmann area 8 based on its unique structural and functional connectivity.
Review in Frontiers in neuroanatomy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- External validation of an integrative model of functional impairment in early-stage behavioral variant frontotemporal dementia (bvFTD).Journal of neurology · 2026Article
- Multimodal Correlates of Longitudinal Functional Decline in Behavioral Variant Frontotemporal Dementia (bvFTD).Journal of personalized medicine · 2026Article
- Mapping the clinical correlates of brain hypoperfusion in behavioral variant frontotemporal dementia: insights from a SPECT imaging study.Frontiers in neuroscience · 2026Article
- Functional Impairment in Behavioral Variant Frontotemporal Dementia: Cognitive, Behavioral, Personality, and Brain Perfusion Contributions.Journal of personalized medicine · 2025Article
- Deconstructing a common pathway concept for Deep Brain Stimulation in the case of Obsessive-Compulsive Disorder.Molecular psychiatry · 2025Article
- Revised cytoarchitectonic mapping of the human premotor cortex identifies seven areas and refines the localisation of frontal eye fields.Communications biology · 2025Article
- Modulatory effect of levodopa on the basal ganglia-cerebellum connectivity in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Children had smaller brain volumes and cortical surface areas after prenatal opioid maintenance therapy exposure.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Evaluation of Theta EEG Neurofeedback Procedure for Cognitive Training Using Simultaneous fMRI in Counterbalanced Active-Sham Study Design.Human brain mapping · 2025Article
- Role for Left Dorsomedial Prefrontal Cortex in Self-Generated, but not Externally Cued, Language Production.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Examining the role of early bilingualism on interference suppression and prefrontal connectivity.Frontiers in integrative neuroscience · 2025Article
- A Dual Role for the Dorsolateral Prefrontal Cortex (DLPFC) in Auditory Deviance Detection.Brain sciences · 2024Article
- Harnessing the frontal aslant tract's structure to assess its involvement in cognitive functions: new insights from 7-T diffusion imaging.Scientific reports · 2024Article
- Structural changes in eloquent cortex secondary to glioma in sensorimotor area.Human brain mapping · 2024Article
- Validation of real-time fMRI neurofeedback procedure for cognitive training using counterbalanced active-sham study design.NeuroImage · 2024Article
- The Brain Connectome for Clinical Neuroscience.Advances in experimental medicine and biology · 2024Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brodmann area 8 (BA8) is traditionally defined as the prefrontal region of the human cerebrum just anterior to the premotor cortices and enveloping most of the superior frontal gyrus. Early studies have suggested the frontal eye fields are situated at its most caudal aspect, causing many to consider BA8 as primarily an ocular center which controls contralateral gaze and attention. However, years of refinement in cytoarchitectural studies have challenged this traditional anatomical definition, providing a refined definition of its boundaries with neighboring cortical areas and the presence of meaningful subdivisions. Furthermore, functional imaging studies have suggested its involvement in a diverse number of higher-order functions, such as motor, cognition, and language. Thus, our traditional working definition of BA8 has likely been insufficient to truly understand the complex structural and functional significance of this area. Recently, large-scale multi-modal neuroimaging approaches have allowed for improved mapping of the neural connectivity of the human brain. Insight into the structural and functional connectivity of the brain connectome, comprised of large-scale brain networks, has allowed for greater understanding of complex neurological functioning and pathophysiological diseases states. Simultaneously, the structural and functional connectivity of BA8 has recently been highlighted in various neuroimaging studies and detailed anatomic dissections. However, while Brodmann's nomenclature is still widely used today, such as for clinical discussions and the communication of research findings, the importance of the underlying connectivity of BA8 requires further review.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.