Evidence map›Paper›PMID 37426894›Full record

ArticleBioactive materials2023

Enhanced osseointegration of drug eluting nanotubular dental implants: An

Pankaj Chauhan, Alok Srivastava, Pooja Bhati, Manish Chaturvedi, Vinay Patil, Sriram Kunnoth, Nisha Kumari, Vedpal Arya, Madhur Pandya, Mohit Agarwal and 6 more

Abstract read
In one paragraph

Article in Bioactive materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Pankaj ChauhanHomi Bhabha Cancer Hospital and Research Centre, Vizag, Andhra Pradesh, India.
Alok SrivastavaDepartment of Mechanical Engineering, Indian Institute of Technology Delhi, India.
Pooja BhatiDepartment of Mechanical Engineering, Indian Institute of Technology Delhi, India.
Manish ChaturvediDepartment of Mechanical Engineering, Indian Institute of Technology Delhi, India.
Vinay PatilDepartment of Mechanical Engineering, Indian Institute of Technology Delhi, India.
Sriram KunnothApplied Mechanics, Indian Institute of Technology Delhi, India.
Nisha KumariDepartment of Mechanical Engineering, Indian Institute of Technology Delhi, India.
Vedpal AryaDepartment of Mechanical Engineering, Indian Institute of Technology Delhi, India.
Madhur PandyaDepartment of Mechanical Engineering, Indian Institute of Technology Delhi, India.
Mohit AgarwalDepartment of Mechanical Engineering, Indian Institute of Technology Delhi, India.
Smiti BhardwajDepartment of Periodontics, Maulana Azad Institute of Dental Sciences, New Delhi, India.
Farrukh FarazDepartment of Periodontics, Maulana Azad Institute of Dental Sciences, New Delhi, India.
Sanjay ChauhanRajasthan Dental College and Hospital, Jaipur, Rajasthan, India.
Mahesh VermaDepartment of Prosthodontics, Maulana Azad Institute of Dental Sciences, New Delhi, India.
Veena KoulCentre for Biomedical Engineering, Indian Institute of Technology Delhi, India.
Naresh BhatnagarDepartment of Mechanical Engineering, Indian Institute of Technology Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Faster and predictable osseointegration is crucial for the success of dental implants, especially in patients with compromised local or systemic conditions. Despite various surface modifications on the commercially available Titanium (Ti) dental implants, the bioactivity of Ti is still low. Thus, to achieve both biological and therapeutic activity on titanium surfaces, surface modification techniques such as titanium nanotubes have been studied as nanotube surfaces can hold therapeutic drugs and molecules. The main aim of the present research work is to study the early osseointegration around the novel Simvastatin drug eluting nanotubular dental implant. In the present research, the titanium nanotubes were fabricated on the screw-shaped dental implant surface and the Simvastatin drug was loaded into the nanotubes using the ultrasonication dip method

Indexed as

BiocompatibilityHistopathologyMicro CTNanoscaleNanotubeSimvastatinTitanium

Identifiers

PMID37426894
PMCPMC10329101

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.