Evidence map›Paper›PMID 37426686›Full record

ArticleClinical case reports2023

Secondary cardiac amyloidosis in a patient with mixed connective tissue disease: A case report.

Ujjwal Prakash Khanal, Prinska Ghimire, Tejash Shahi, Tulsi Ram Dhakal, Saket Jha

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ujjwal Prakash KhanalInstitute of Medicine, Tribhuwan University Teaching Hospital Kathmandu Nepal.ORCID https://orcid.org/0000-0002-9707-1184
Prinska GhimireInstitute of Medicine, Tribhuwan University Teaching Hospital Kathmandu Nepal.ORCID https://orcid.org/0000-0003-0848-8322
Tejash ShahiInstitute of Medicine, Tribhuwan University Teaching Hospital Kathmandu Nepal.
Tulsi Ram DhakalInstitute of Medicine, Tribhuwan University Teaching Hospital Kathmandu Nepal.
Saket JhaInstitute of Medicine, Tribhuwan University Teaching Hospital Kathmandu Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 62-year-old man who presented with shortness of breath, cough, bilateral lower limbs' swelling, and blackish discoloration of multiple fingertips over the past 2 months. Anti-Ribonucleoprotein antibodies were found to be present, and gadolinium-based cardiac MRI showed non-vascular subendocardial enhancement with diffuse symmetrical thickening of the left ventricular wall. A diagnosis of Mixed connective tissue disease with secondary cardiac amyloidosis was thus made, and the patient was successfully managed with intravenous cyclophosphamide, corticosteroids, and other supportive measures. Although extremely rare, this case shows that secondary cardiac amyloidosis should be considered while managing patients with MCTD.

Indexed as

amyloidosisheart failuremixed connective tissue diseasesystemic lupus erythematosus

Identifiers

PMID37426686
PMCPMC10323719

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.