Evidence map›Paper›PMID 37426656›Full record

ReviewFrontiers in immunology2023

Inflammation in multiple system atrophy.

Marta Leńska-Mieciek, Natalia Madetko-Alster, Piotr Alster, Leszek Królicki, Urszula Fiszer, Dariusz Koziorowski

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marta Leńska-MieciekDepartment of Neurology and Epileptology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Natalia Madetko-AlsterDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Piotr AlsterDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Leszek KrólickiDepartment of Nuclear Medicine, Medical University of Warsaw, Warsaw, Poland.
Urszula FiszerDepartment of Neurology and Epileptology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Dariusz KoziorowskiDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Medical University of Warsaw · PLPostgraduate School of Molecular Medicine · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Misfolding protein aggregation inside or outside cells is the major pathological hallmark of several neurodegenerative diseases. Among proteinopathies are neurodegenerative diseases with atypical Parkinsonism and an accumulation of insoluble fibrillary alpha-synuclein (synucleinopathies) or hyperphosphorylated tau protein fragments (tauopathies). As there are no therapies available to slow or halt the progression of these disea ses, targeting the inflammatory process is a promising approach. The inflammatory biomarkers could also help in the differential diagnosis of Parkinsonian syndromes. Here, we review inflammation's role in multiple systems atrophy pathogenesis, diagnosis, and treatment.

Indexed as

Multiple System AtrophyParkinsonian DisordersSynucleinopathiesTauopathiesHumansInflammationinflammationmultiple system atrophy (MSA)neurodegenerationsynucleinopathiestauopathies

Identifiers

PMID37426656
PMCPMC10327640
OpenAlexW4381929894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.