Evidence map›Paper›PMID 37426597›Full record

ArticleTranslational andrology and urology2023

Risk factors and predictors of urogenous sepsis after percutaneous nephrolithotomy for idiopathic calcium oxalate nephrolithiasis.

Xinfeng Chen, Siqi Li, Chunmei Shi, Wei Zhang, Zhenmin Liu, Jie Jiang, Yong Zhang, Zhan Chen, Bing Zheng, Hua Zhu

Open access · diamondAbstract read
In one paragraph

Article in Translational andrology and urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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  9. Porous Se@SiOTranslational andrology and urology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xinfeng ChenDepartment of Urology Surgery, The Second Affiliated Hospital of Nantong University, Nantong, China.
Siqi LiDepartment of Urology Surgery, The Second Affiliated Hospital of Nantong University, Nantong, China.
Chunmei ShiDepartment of Urology Surgery, The Second Affiliated Hospital of Nantong University, Nantong, China.
Wei ZhangDepartment of Urology Surgery, The Second Affiliated Hospital of Nantong University, Nantong, China.
Zhenmin LiuDepartment of Urology Surgery, The Second Affiliated Hospital of Nantong University, Nantong, China.
Jie JiangDepartment of Urology Surgery, The Second Affiliated Hospital of Nantong University, Nantong, China.
Yong ZhangDepartment of Urology Surgery, The Second Affiliated Hospital of Nantong University, Nantong, China.
Zhan ChenDepartment of Urology Surgery, The Second Affiliated Hospital of Nantong University, Nantong, China.
Bing ZhengDepartment of Urology Surgery, The Second Affiliated Hospital of Nantong University, Nantong, China.
Hua ZhuDepartment of Urology Surgery, The Second Affiliated Hospital of Nantong University, Nantong, China.
Affiliated Hospital of Nantong University · CNSecond Affiliated Hospital of Nantong UniversityNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this study was to use bioinformatics approaches to screen and identify the key genes of idiopathic calcium oxalate nephrolithiasis, and explore its potential molecular mechanism. Methods: The GSE73680 kidney stone data set was downloaded from the Gene Expression Omnibus (GEO). R software (The R Foundation for Statistical Computing) was used to screen differentially expressed genes. GeneMANIA and Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) databases were used to analyze related genes interacting with crucial genes, and a protein-protein interaction (PPI) network was constructed. The differential genes were then subjected to the Gene Ontology (GO) functional annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) signaling pathway enrichment analysis using the Database for Annotation, Visualization, and Integrated Discovery (DAVID) database. The clinical data of 156 patients who received percutaneous nephrolithotomy (PCNL) therapy at our facility between January 2013 and December 2017 were retrospectively analyzed. The various parameters associated with postoperative urogenous sepsis were identified using multivariable logistic regression analysis. Results: The study discovered one differentially expressed gene was nucleotide-binding oligomerization domain-containing protein 2 ( Conclusions: Preoperative urinary nitrite positive status, postoperative WBC count ≥2.98×10

Indexed as

bioinformaticsidiopathic calcium oxalate nephrolithiasisPercutaneous nephrolithotomy (PCNL)predictorsurogenous sepsis

Identifiers

PMID37426597
PMCPMC10323449
OpenAlexW4382400263

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.