Evidence map›Paper›PMID 37426583›Full record

ArticleDigital health

Analysis of the effect of glutamyltransferase on hyperlipidemia based on decision tree.

Tingting Zhang, Dantong Ouyang, Chenglin Sun, Yaru Bi, Lili He, Hongtao Bai

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Article in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Tingting ZhangCollege of Computer Science and Technology, Jilin University, Changchun, China.ORCID https://orcid.org/0000-0002-0193-058X
Dantong OuyangCollege of Computer Science and Technology, Jilin University, Changchun, China.
Chenglin SunDepartment of Endocrinology and Metabolism, First Hospital of Jilin University, Changchun, China.
Yaru BiDepartment of Endocrinology and Metabolism, First Hospital of Jilin University, Changchun, China.
Lili HeCollege of Computer Science and Technology, Jilin University, Changchun, China.
Hongtao BaiSymbol Computation and Knowledge Engineer of Ministry of Education, Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study is designed to analyze the potential influencing factors of hyperlipidemia, and to explore the relationship between liver function indicators such as gamma-glutamyltransferase (GGT) and hyperlipidemia. Methods: Data were derived from 7599 outpatients who visited the Department of Endocrinology of the First Hospital of Jilin University (2017-2019). A multinomial regression model is used to identify related factors of hyperlipidemia and the decision tree method is used to explore the general rules in hyperlipidemia patients and non-hyperlipidemia patients on these factors. Results: The average of age, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure, aspartate aminotransferase, alanine aminotransferase (ALT), GGT and glycosylated hemoglobin (HbA1c) in the hyperlipidemia group are higher than those in the non-hyperlipidemia group. In multiple regression analysis, SBP, BMI, fasting plasma glucose, 2-h postprandial blood glucose, HbA1c, ALT, GGT are associated with triglyceride. For people with HbA1c less than 6.0%, controlling GGT within 30 IU/L reduces the prevalence of hypertriglyceridemia by 4%, and for people with metabolic syndrome with impaired glucose tolerance controlling GGT within 20 IU/L reduces the prevalence of hypertriglyceridemia by 11%. Conclusions: Even when GGT is in the normal range, the prevalence of hypertriglyceridemia increases with its gradual increase. Controlling GGT in people with normoglycemia and impaired glucose tolerance can reduce the risk of hyperlipidemia.

Indexed as

decision treeGlutamyltransferasehyperlipidemiapreventionpublic health

Identifiers

PMID37426583
PMCPMC10328008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.