Evidence map›Paper›PMID 37425787›Full record

ArticlebioRxiv : the preprint server for biology2023

The Host Adapted Fungal Pathogens of

Ousmane H Cissé, Shelly Curran, H Diego Folco, Yueqin Liu, Lisa Bishop, Honghui Wang, Elizabeth R Fischer, A Sally Davis, Spenser Babb-Biernacki, Vinson P Doyle and 9 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

Ousmane H CisséCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Shelly CurranCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
H Diego FolcoLaboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Yueqin LiuCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Lisa BishopCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Honghui WangCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Elizabeth R FischerMicroscopy Unit, Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
A Sally DavisDiagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine, Manhattan, USA.
Spenser Babb-BiernackiMuseum of Natural Science and Department of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana, USA.
Vinson P DoyleDepartment of Plant Pathology and Crop Physiology, Lousiana State University AgCenter, Baton Rouge, Louisiana, USA.
Jonathan K RichardsDepartment of Plant Pathology and Crop Physiology, Lousiana State University AgCenter, Baton Rouge, Louisiana, USA.
Sergio A HassanBioinformatics and Computational Biosciences Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
John P DekkerBacterial Pathogenesis and Antimicrobial Resistance Unit, National Institute of Allergy, and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Pavel P KhilBacterial Pathogenesis and Antimicrobial Resistance Unit, National Institute of Allergy, and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Jason M BrenchleyLaboratory of Viral Diseases, National Institute of Allergy, and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Shiv GrewalLaboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Melanie CushionDepartment of Internal Medicine, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Liang MaCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Joseph A KovacsCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
National Institutes of Health Clinical Center · USNational Institutes of Health · USLouisiana State University Agricultural Center · USKansas State University · USLouisiana State University · USUniversity of Cincinnati Medical Center · US

Funding

BLR&D Research Career Scientist Award ApplicationIK6BX005232 · VA · CINCINNATI VA MEDICAL CENTER RESEARCH · PI Melanie T Cushion · 2020 to 2026
–
BLRD VA IK6 BX005232
6 · The paper itself

Abstract

Centromeres are genomic regions that coordinate accurate chromosomal segregation during mitosis and meiosis. Yet, despite their essential function, centromeres evolve rapidly across eukaryotes. Centromeres are often the sites of chromosomal breaks which contribute to genome shuffling and promote speciation by inhibiting gene flow. How centromeres form in strongly host-adapted fungal pathogens has yet to be investigated. Here, we characterized the centromere structures in closely related species of mammalian-specific pathogens of the fungal phylum of Ascomycota. Methods allowing reliable continuous culture of

Identifiers

PMID37425787
PMCPMC10327204
OpenAlexW4376273118

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.