Evidence map›Paper›PMID 37425745›Full record

ArticlebioRxiv : the preprint server for biology2023

Dysregulated Pulmonary Inflammatory Responses Exacerbate the Outcome of Secondary Aspergillosis Following Influenza.

Chrono K Lee, Lorena V N Oliveira, Ali Akalin, Charles A Specht, Diana Lourenco, Christina L Gomez, Zaida G Ramirez-Ortiz, Jennifer P Wang, Stuart M Levitz

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Chrono K LeeDepartment of Medicine, The University of Massachusetts Chan Medical School, Worcester, MA, United States.
Lorena V N OliveiraDepartment of Medicine, The University of Massachusetts Chan Medical School, Worcester, MA, United States.
Ali AkalinDepartment of Pathology, The University of Massachusetts Chan Medical School, Worcester, MA, United States.
Charles A SpechtDepartment of Medicine, The University of Massachusetts Chan Medical School, Worcester, MA, United States.
Diana LourencoDepartment of Medicine, The University of Massachusetts Chan Medical School, Worcester, MA, United States.
Christina L GomezDepartment of Medicine, The University of Massachusetts Chan Medical School, Worcester, MA, United States.
Zaida G Ramirez-OrtizDepartment of Medicine, The University of Massachusetts Chan Medical School, Worcester, MA, United States.
Jennifer P WangDepartment of Medicine, The University of Massachusetts Chan Medical School, Worcester, MA, United States.
Stuart M LevitzDepartment of Medicine, The University of Massachusetts Chan Medical School, Worcester, MA, United States.
University of Massachusetts Chan Medical School · US

Funding

Preclinical studies of a Cryptococcus vaccine for AIDS patientsR01AI125045 · NIAID · WASHINGTON UNIVERSITY · PI LEVITZ, STUART MICHAEL, LODGE, JENNIFER K. · 2016 to 2025
$7.1M
A subunit Cryptococcus vaccineR01AI172154 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Stuart Michael Levitz · 2022 to 2026
$3.1M
The contribution of eosinophils and the IL-23/IL-17 axis to host responses to AspergillusR01AI139615 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEVITZ, STUART MICHAEL · 2018 to 2021
$1.7M
NIAID NIH HHS R01 AI125045NIAID NIH HHS R01 AI139615NIAID NIH HHS R01 AI172154
6 · The paper itself

Abstract

Inhalation of airborne conidia of the ubiquitous fungus Importance: Severe influenza is a risk factor for fatal invasive pulmonary aspergillosis; however, the mechanistic basis for the lethality is unclear. Utilizing an influenza-associated pulmonary aspergillosis (IAPA) model, we found that mice infected with influenza A virus followed by

Identifiers

PMID37425745
PMCPMC10326983
OpenAlexW4382653453

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.