Evidence map›Paper›PMID 37425682›Full record

ArticlebioRxiv : the preprint server for biology2024

A computational model predicts sex-specific responses to calcium channel blockers in mammalian mesenteric vascular smooth muscle.

Gonzalo Hernandez-Hernandez, Samantha C O'Dwyer, Collin Matsumoto, Mindy Tieu, Zhihui Fong, Pei-Chi Yang, Timothy J Lewis, L Fernando Santana, Colleen E Clancy

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Gonzalo Hernandez-HernandezDepartment of Physiology & Membrane Biology, Center for Precision Medicine and Data Science, University of California School of Medicine, Davis, California, 95616.ORCID 0000-0001-6940-9005
Samantha C O'DwyerDepartment of Physiology & Membrane Biology, Center for Precision Medicine and Data Science, University of California School of Medicine, Davis, California, 95616.ORCID 0000-0001-5334-9984
Collin MatsumotoDepartment of Physiology & Membrane Biology, Center for Precision Medicine and Data Science, University of California School of Medicine, Davis, California, 95616.ORCID 0000-0002-5370-1156
Mindy TieuDepartment of Physiology & Membrane Biology, Center for Precision Medicine and Data Science, University of California School of Medicine, Davis, California, 95616.
Zhihui FongDepartment of Physiology & Membrane Biology, Center for Precision Medicine and Data Science, University of California School of Medicine, Davis, California, 95616.ORCID 0000-0002-0521-0088
Pei-Chi YangDepartment of Physiology & Membrane Biology, Center for Precision Medicine and Data Science, University of California School of Medicine, Davis, California, 95616.ORCID 0000-0002-5753-1131
Timothy J LewisDepartment of Mathematics, University of California, Davis, California, 95616.
L Fernando SantanaDepartment of Physiology & Membrane Biology, Center for Precision Medicine and Data Science, University of California School of Medicine, Davis, California, 95616.ORCID 0000-0002-4297-8029
Colleen E ClancyDepartment of Physiology & Membrane Biology, Center for Precision Medicine and Data Science, University of California School of Medicine, Davis, California, 95616.ORCID 0000-0001-6849-4885
Precision for Medicine (United States) · USUniversity of California, Davis · US

Funding

Training Program In Basic & Translational Cardiovascular ScienceT32HL086350 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Martin Cadeiras, David A. Liem · 2008 to 2026
$7.1M
Development of the Predictive NeuroCardiovascular SimulatorOT2OD026580 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CLANCY, COLLEEN E, GRANDI, ELEONORA · 2018 to 2021
$5.7M
In silico Safety PharmacologyR01HL128537 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CLANCY, COLLEEN E, SANTANA, LUIS F · 2016 to 2024
$5.7M
Multi-Scale Modeling of Vascular Signaling UnitsR01HL152681 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CLANCY, COLLEEN E, SANTANA, LUIS F · 2020 to 2023
$2.4M
NHLBI NIH HHS R01 HL128537NHLBI NIH HHS R01 HL152681NHLBI NIH HHS T32 HL086350NIH HHS OT2 OD026580
6 · The paper itself

Abstract

The function of the smooth muscle cells lining the walls of mammalian systemic arteries and arterioles is to regulate the diameter of the vessels to control blood flow and blood pressure. Here, we describe an

Identifiers

PMID37425682
PMCPMC10327109
OpenAlexW4382049076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.