Evidence map›Paper›PMID 37425463›Full record

ArticleJTCVS open2023

Effect of venoarterial extracorporeal membrane oxygenation initiation timing on tricuspid valve surgery outcomes.

Amy Hembree, Matthew Lawlor, Samantha Nemeth, Sivagowry Rasalingam Mørk, Yuji Kaku, Jessica Spellman, Andrea Miltiades, Paul Kurlansky, Koji Takeda, Isaac George

Open access · goldAbstract read
In one paragraph

Article in JTCVS open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Current insights on temporary mechanical circulatory support in adults with post-cardiotomy cardiogenic shock.European heart journal supplements : journal of the European Society of Cardiology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Amy HembreeDivision of Cardiac, Thoracic, and Vascular Surgery, New York Presbyterian Hospital-Columbia University Irving Medical Center, New York, NY.
Matthew LawlorDivision of Cardiology, New York Presbyterian Hospital-Columbia University Irving Medical Center, New York, NY.
Samantha NemethDepartment of Surgery, Center for Innovation and Outcome Research, New York Presbyterian Hospital-Columbia University Irving Medical Center, New York, NY.
Sivagowry Rasalingam MørkDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Yuji KakuDivision of Cardiac, Thoracic, and Vascular Surgery, New York Presbyterian Hospital-Columbia University Irving Medical Center, New York, NY.
Jessica SpellmanDepartment of Anesthesiology, New York Presbyterian Hospital-Columbia University Irving Medical Center, New York, NY.
Andrea MiltiadesDepartment of Anesthesiology, New York Presbyterian Hospital-Columbia University Irving Medical Center, New York, NY.
Paul KurlanskyDivision of Cardiac, Thoracic, and Vascular Surgery, New York Presbyterian Hospital-Columbia University Irving Medical Center, New York, NY.
Koji TakedaDivision of Cardiac, Thoracic, and Vascular Surgery, New York Presbyterian Hospital-Columbia University Irving Medical Center, New York, NY.
Isaac GeorgeDivision of Cardiac, Thoracic, and Vascular Surgery, New York Presbyterian Hospital-Columbia University Irving Medical Center, New York, NY.
NewYork–Presbyterian Hospital · USColumbia University · USNew York Hospital Queens · USAarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Tricuspid valve surgery is associated with high rates of shock and in-hospital mortality. Early initiation of venoarterial extracorporeal membrane oxygenation after surgery may provide right ventricular support and improve survival. We evaluated mortality in patients undergoing tricuspid valve surgery based on the timing of venoarterial extracorporeal membrane oxygenation. Methods: All consecutive adult patients undergoing isolated or combined surgical tricuspid valve repair or replacement from 2010 to 2022 requiring venoarterial extracorporeal membrane oxygenation use were stratified by initiation in the operating room (Early) versus outside of the operating room (Late). Variables associated with in-hospital mortality were explored using logistic regression. Results: There were 47 patients who required venoarterial extracorporeal membrane oxygenation: 31 Early and 16 Late. Mean age was 55.6 years (standard deviation, 16.8), 25 (54.3%) were in New York Heart Association class III/IV, 30 (60.8%) had left-sided valve disease, and 11 (23.4%) had undergone prior cardiac surgery. Median left ventricular ejection fraction was 60.0% (interquartile range, 45-65), right ventricular size was moderately to severely increased in 26 patients (60.5%), and right ventricular function was moderately to severely reduced in 24 patients (51.1%). Concomitant left-sided valve surgery was performed in 25 patients (53.2%). There were no differences in baseline characteristics or invasive measurements immediately before surgery between the Early and Late groups. Venoarterial extracorporeal membrane oxygenation was initiated 194 (23.0-840.0) minutes after cardiopulmonary bypass in the Late venoarterial extracorporeal membrane oxygenation group. In-hospital mortality was 35.5% (n = 11) in the Early group versus 68.8% (n = 11) in the Late group ( Conclusions: Early postoperative initiation of venoarterial extracorporeal membrane oxygenation after tricuspid valve surgery in high-risk patients may be associated with improvement in postoperative hemodynamics and in-hospital mortality.

Indexed as

heart failuretricuspid valve regurgitationVA-ECMO

Identifiers

PMID37425463
PMCPMC10328813
OpenAlexW4322621384

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.