ArticleClinical ophthalmology (Auckland, N.Z.)2023
Four-Year Outcome of XEN 45 Gel Stent Implantation in a Swedish Population.
Article in Clinical ophthalmology (Auckland, N.Z.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of XEN gel stent for management of open-angle glaucoma: a systematic review and meta-analysis.PeerJ · 2026Pooled it
- Predicting bleb revision after XEN gel stent surgery in a real-world open-angle glaucoma cohort.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Novel Non-Valved Glaucoma Drainage Device with Reduced Inner Lumen Diameter: 6-Month Safety and Efficacy Outcomes.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Efficacy and Safety of Open-Conjunctiva Ab Externo 63 µm vs. 45 µm XENJournal of clinical medicine · 2025Article
- Complications of XEN gel stent implantation for the treatment of glaucoma: a systematic review.Frontiers in medicine · 2024Review
- Intraocular Pressure and Medication Outcomes of a Novel Primary Trimming Technique for XEN Gel Stent.Journal of current glaucoma practiceArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To report the long-time success rate of XEN 45 gel stent implantation in a Scandinavian population. Patients and Methods: This was a retrospective single-center analysis of all patients undergoing XEN 45 stent surgery between December 2015 and May 2017. The main outcome was success rate according to several definitions of success. Subgroup analysis was performed. Secondary outcomes were change in intraocular pressure (IOP) and number of IOP-lowering agents. Need for secondary glaucoma surgery, needling rate and complications were recorded. Results: A total of 103 eyes could be evaluated after four years. Mean age was 70.6 years. Primary open-angle glaucoma (POAG) accounted for 46.6% and exfoliative glaucoma (PEXG) for 39.8%. Mean IOP dropped from 24.0 to 15.9 mmHg (p<0.001) and IOP-lowering agents from 3.5 to 1.5 (p<0.001). The success rate with individual target pressures after four years was 43.7%. Secondary glaucoma surgery was performed in 45 (43.7%) of cases. Combined cases (n=12) were not statistically different to stand-alone procedures (p=0.28). No difference between PEXG and POAG could be detected (p=0.44). During the learning curve, stent misplacement was common and resulted in worse outcome for less experienced surgeons. Conclusion: The overall success rate of XEN 45 gel stent surgery in the present cohort is relatively low in a long-time follow-up under the given circumstances if all initial patients are included to follow-up. The influence of the surgeon's learning curve is obvious, and improvement in success can be expected when used by experienced and high-volume surgeons. No significant differences were found in PEXG compared to POAG or in XEN surgery combined with cataract surgery compared to stand-alone.
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