Evidence map›Paper›PMID 37424834›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2023

Eye-Lens Dose Reduction using Region of Interest (ROI) Attenuators in Neuroimaging.

Martina P Orji, Chao Guo, Zhenyu Xiong, S V Setlur Nagesh, Stephen Rudin, Daniel R Bednarek

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Martina P OrjiUniversity at Buffalo, Canon Stroke and Vascular Research Center, Buffalo, NY, USA.
Chao GuoCedars Sinai Medical Center, S. Mark Taper Foundation Imaging Center, Los Angeles, CA, USA.
Zhenyu XiongRutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
S V Setlur NageshUniversity at Buffalo, Canon Stroke and Vascular Research Center, Buffalo, NY, USA.
Stephen RudinUniversity at Buffalo, Canon Stroke and Vascular Research Center, Buffalo, NY, USA.
Daniel R BednarekUniversity at Buffalo, Canon Stroke and Vascular Research Center, Buffalo, NY, USA.

Funding

High Speed Angiography at 1000 frames per secondR01EB030092 · NIBIB · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI RUDIN, STEPHEN · 2020 to 2023
$2.6M
NIBIB NIH HHS R01 EB030092
6 · The paper itself

Abstract

Lens dose can be high during neuro-interventional procedures, increasing the risk of cataractogenesis. Although beam collimation can be effective in reducing lens dose, it also restricts the FOV. ROI imaging with a reduced-dose peripheral field permits full-field information with reduced lens dose. This work investigates the magnitude of lens-dose reduction possible with ROI imaging. EGSnrc Monte-Carlo calculations of lens dose were made for the Zubal head phantom as a function of gantry angulation and head shift from isocenter for both large and small FOV's. The lens dose for ROI attenuators of varying transmission was simulated as the weighted sum of the lens dose from the small ROI FOV and that from the attenuated larger FOV. Image intensity and quantum mottle differences between ROI and periphery can be equalized by image processing. The lens dose varies considerably with beam angle, head shift, and field size. For both eyes, the lens-dose reduction with an ROI attenuator increases with LAO angulation, being highest for lateral projections and lowest for PA. For an attenuator with small ROI field (5 × 5 cm) and 20% transmission, the lens dose for lateral projections is reduced by about 75% compared to a full dose 10 ×10 cm FOV, while the reduction ranges between 30 and 40% for PA projections. Use of ROI attenuators can substantially reduce the dose to the lens of the eye for all gantry angles and head shifts, while allowing peripheral information to be seen in a larger FOV.

Indexed as

dose reductioneye lens dosefluoroscopic doseLAO gantry angleNeuro-interventional procedureROI

Identifiers

PMID37424834
PMCPMC10327446

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.