Evidence map›Paper›PMID 37424830›Full record

ArticleAmerican journal of cancer research2023

Rintatolimod: a potential treatment in patients with pancreatic cancer expressing Toll-like receptor 3.

Hassana El Haddaoui, Casper Wf van Eijck, Michail Doukas, Thierry Pp van den Bosch, Peter M van Koetsveld, Leo J Hofland, Dana Am Mustafa, Casper Hj van Eijck

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  4. Article
  5. Recent trends in the delivery of RNA drugs: Beyond the liver, more than vaccine.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hassana El HaddaouiDepartment of Surgery, Erasmus University Medical Center Rotterdam, The Netherlands.
Casper Wf van EijckDepartment of Surgery, Erasmus University Medical Center Rotterdam, The Netherlands.
Michail DoukasDepartment of Pathology, Erasmus University Medical Center Rotterdam, The Netherlands.
Thierry Pp van den BoschDepartment of Pathology, Erasmus University Medical Center Rotterdam, The Netherlands.
Peter M van KoetsveldDepartment of Internal Medicine, Erasmus University Medical Center Rotterdam, The Netherlands.
Leo J HoflandDepartment of Internal Medicine, Erasmus University Medical Center Rotterdam, The Netherlands.
Dana Am MustafaDepartment of Pathology, Tumor Immuno-Pathology Laboratory, Erasmus University Medical Center Rotterdam, The Netherlands.
Casper Hj van EijckDepartment of Surgery, Erasmus University Medical Center Rotterdam, The Netherlands.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer has a dismal prognosis, and treatment options for patients with locally advanced or metastatic disease are limited. Early tumor progression after standard chemo- and or radiotherapy remains a major concern in managing these patients. Treating pancreatic cancer patients with the Toll-like receptor 3 (TLR-3) agonist rintatolimod (Ampligen

Indexed as

cancer cell migrationcancer cell proliferationdirect anti-tumoral effectsPDACrintatolimod (Ampligen®)TLR-3 agonist

Identifiers

PMID37424830
PMCPMC10326577
OpenAlexW4383711420

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.