Evidence map›Paper›PMID 37424803›Full record

ArticleAmerican journal of cancer research2023

The splicing factor proline and glutamine rich promotes the growth of osteosarcoma via the c-Myc signaling pathway.

Lianghao Mao, Pan Jiang, Xuan Lei, Bing Zhang, Xinyu Zhong, Zhengyu Yin, Yongjie Wang, Dapeng Li, Yiming Zhang, Qiping Zheng

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 3 countries.

Lianghao MaoAffiliated Hospital of Jiangsu University Zhenjiang 212001, Jiangsu, China.
Pan JiangAffiliated Hospital of Jiangsu University Zhenjiang 212001, Jiangsu, China.
Xuan LeiAffiliated Hospital of Jiangsu University Zhenjiang 212001, Jiangsu, China.
Bing ZhangAffiliated Hospital of Jiangsu University Zhenjiang 212001, Jiangsu, China.
Xinyu ZhongAffiliated Hospital of Jiangsu University Zhenjiang 212001, Jiangsu, China.
Zhengyu YinAffiliated Hospital of Jiangsu University Zhenjiang 212001, Jiangsu, China.
Yongjie WangDepartment of Orthopedic Surgery, Shanghai Tenth People's Hospital Affiliated to Tongji University Shanghai 200072, China.
Dapeng LiAffiliated Hospital of Jiangsu University Zhenjiang 212001, Jiangsu, China.
Yiming ZhangAffiliated Hospital of Jiangsu University Zhenjiang 212001, Jiangsu, China.
Qiping ZhengDepartment of Laboratory Science, School of Medicine, Jiangsu University Zhenjiang 212013, Jiangsu, China.
Jiangsu University · CNShanghai Tenth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Splicing factor proline- and glutamine-rich (SFPQ) regulates transcripts in skeletal muscle metabolism and tumorigenesis. As osteosarcoma (OS) is the most common malignant bone tumor characterized by genome instability, such as MYC amplification, this study aimed to investigate the role and mechanism of SFPQ in OS. Expression of SFPQ in OS cell lines and human OS tissues was detected using quantitative real-time PCR, western blot, and fluorescence

Indexed as

c-Myc signalingosteosarcomaprogressionSplicing factor proline- and glutamine-rich (SFPQ)

Identifiers

PMID37424803
PMCPMC10326564
OpenAlexW4383709941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.