ArticleFrontiers in cellular and infection microbiology2023
Metabolic pathway prediction of core microbiome based on enterotype and orotype.
Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Antibiotic exposure during weaning disrupts oral microbiota assembly in piglets.Journal of animal science and biotechnology · 2026Article
- Classification of the tongue microbiota and its associations with lifestyle factors and health status.NPJ biofilms and microbiomes · 2026Article
- The oral-gut microbiota axis: a link in cardiometabolic diseases.NPJ biofilms and microbiomes · 2025Review
- Oral microbial signatures underlying recurrence via PI3K/AKT/mTOR pathway modulation in oral squamous cell carcinoma.Journal of oral microbiology · 2025Article
- The importance of gut microbiome in the perinatal period.European journal of pediatrics · 2024Review
- Enterotype-Specific Effects of Red Beetroot (Life (Basel, Switzerland) · 2024Article
- The gut mycobiome signatures in long-lived populations.iScience · 2024Article
- Comparison of the performance of MiSeq and NovaSeq in oral microbiome study.Journal of oral microbiology · 2024Article
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Authors and funding
5 authors.
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Abstract
Introduction: Identification of key microbiome components has been suggested to help address the maintenance of oral and intestinal health in humans. The core microbiome is similar in all individuals, whereas the diverse microbiome varies across individuals, based on their unique lifestyles and phenotypic and genotypic determinants. In this study, we aimed to predict the metabolism of core microorganisms in the gut and oral environment based on enterotyping and orotyping. Materials and methods: Gut and oral samples were collected from 83 Korean women aged 50 years or older. The extracted DNA was subjected to next-generation sequencing analysis of 16S rRNA hypervariable regions V3-V4. Results: Gut bacteria were clustered into three enterotypes, while oral bacteria were clustered into three orotypes. Sixty-three of the core microbiome between the gut and oral population were correlated, and different metabolic pathways were predicted for each type. Conclusion: Overall, the study suggested that collapsing the human body's multidimensional microbiome into a few categories may help characterize the microbiomes better and address health issues more deeply.
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