Evidence map›Paper›PMID 37424485›Full record

ArticleNeuroRehabilitation2023

Venous thromboembolism and anticoagulation in spinal cord lesion rehabilitation inpatients: A 10-year retrospective study.

Vadim Bluvshtein, Amiram Catz, Ala Mahamid, Keren Elkayam, Dianne Michaeli, Lilach Front, Adi Kfir, Ilana Gelernter, Elena Aidinoff

Open access · bronzeAbstract read
In one paragraph

Article in NeuroRehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Vadim BluvshteinDepartment of Spinal Rehabilitation, Loewenstein Rehabilitation Medical Center, Raanana, Israel.
Amiram CatzDepartment of Spinal Rehabilitation, Loewenstein Rehabilitation Medical Center, Raanana, Israel.
Ala MahamidDepartment of Spinal Rehabilitation, Loewenstein Rehabilitation Medical Center, Raanana, Israel.
Keren ElkayamDepartment of Spinal Rehabilitation, Loewenstein Rehabilitation Medical Center, Raanana, Israel.
Dianne MichaeliDepartment of Spinal Rehabilitation, Loewenstein Rehabilitation Medical Center, Raanana, Israel.
Lilach FrontDepartment of Spinal Rehabilitation, Loewenstein Rehabilitation Medical Center, Raanana, Israel.
Adi KfirDepartment of Spinal Rehabilitation, Loewenstein Rehabilitation Medical Center, Raanana, Israel.
Ilana GelernterSchool of Mathematical Sciences, Tel Aviv University, Tel Aviv, Israel.
Elena AidinoffSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Loewenstein Hospital Rehabilitation Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVenous thromboembolism (VTE) is a concern following the onset of spinal cord lesions (SCL).

objectivesTo assess the current efficacy and risks of anticoagulation after SCL and consider changes in thromboprophylaxis.

methodsThis retrospective cohort study included individuals admitted to inpatient rehabilitation within 3 months of SCL onset. Main outcome measures were the incidence of deep vein thrombosis (DVT), pulmonary embolism (PE), bleeding, thrombocytopenia, or death, which occurred within 1 year of the SCL onset.

resultsVTE occurred in 37 of the 685 patients included in the study (5.4%, 95% CI 3.7-7.1%, 2.8% PE), and in 16 of 526 patients who received prophylactic anticoagulation at rehabilitation (3%, 95% CI 1.6-4.5%, 1.1% PE, with at least 1 fatality). Of these 526, 1.3% developed clinically significant bleeding and 0.8% thrombocytopenia. Prophylactic anticoagulation, most commonly 40 mg/day, continued until a median period of 6.4 weeks after SCL onset (25% -75% percentiles 5.8-9.7), but in 29.7%, VTE occurred more than 3 months after SCL onset.

conclusionThe VTE prophylaxis used for the present cohort contributed to a considerable but limited reduction of VTE incidence. The authors recommend conducting a prospective study to assess the efficacy and safety of an updated preventive anticoagulation regimen.

Indexed as

Pulmonary EmbolismThrombocytopeniaVenous ThromboembolismAnticoagulantsHumansInpatientsProspective StudiesRetrospective StudiesSpinal CordAnticoagulantsanticoagulationDeep vein thrombosisprophylaxispulmonary embolismspinal cord lesions

Identifiers

PMID37424485
PMCPMC10473086
OpenAlexW4383066718

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.