Evidence map›Paper›PMID 37424170›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

The NLRP11 Protein Bridges the Histone Lysine Acetyltransferase KAT7 to Acetylate Vimentin in the Early Stage of Lung Adenocarcinoma.

Rui Yang, Weilin Peng, Shuai Shi, Xiong Peng, Qidong Cai, Zhenyu Zhao, Boxue He, Guangxu Tu, Wei Yin, Yichuan Chen and 5 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Rui YangDepartment of Pathology, Xiangya Hospital and School of Basic Medicine, Central South University, Changsha, Hunan, 410008, China.
Weilin PengDepartment of Thoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Shuai ShiDepartment of Thoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Xiong PengDepartment of Thoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Qidong CaiDepartment of Thoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Zhenyu ZhaoDepartment of Thoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Boxue HeDepartment of Thoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Guangxu TuDepartment of Thoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Wei YinDepartment of Thoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Yichuan ChenDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Yuqian ZhangDepartment of Thoracic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310000, China.
Fang LiuClinic Nursing Teaching and Research Section, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Xiang WangDepartment of Thoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Desheng XiaoDepartment of Pathology, Xiangya Hospital and School of Basic Medicine, Central South University, Changsha, Hunan, 410008, China.
Yongguang TaoDepartment of Pathology, Xiangya Hospital and School of Basic Medicine, Central South University, Changsha, Hunan, 410008, China.ORCID 0000-0003-2354-5321
Central South University · CNFirst Affiliated Hospital Zhejiang University · CN

Funding

Central South University Research Program of Advanced Interdisciplinary Studies 2023QYJC030Graduate research innovation project of Central South University 1053320190396Hunan Provincial Key Area R&D Programs 2019SK2253Hunan Provincial Key Area R&D Programs 2020SK53424Hunan Provincial Key Area R&D Programs 2021JJ30957Hunan Provincial Key Area R&D Programs 2021SK2013Hunan Provincial Key Area R&D Programs 2021SK2020Hunan Provincial Key Area R&D Programs S2021JJMSXM2846National Natural Science Foundation of China 81972195National Natural Science Foundation of China 82072594National Natural Science Foundation of China 82073097National Natural Science Foundation of China 82073136National Natural Science Foundation of China 82172879National Natural Science Foundation of China 82272982Natural Science Foundation of Hunan ProvinceScience and Technology Innovation Program of Hunan Province 2022RC3072Scientific Research Program of Hunan Provincial Health Commission 20201047
6 · The paper itself

Abstract

Accumulation of vimentin is the core event in epithelial-mesenchymal transition (EMT). Post-translational modifications have been widely reported to play crucial roles in imparting different properties and functions to vimentin. Here, a novel modification of vimentin, acetylated at Lys

Indexed as

Adenocarcinoma of LungLung NeoplasmsHistone AcetyltransferasesHistonesHumansLysineVimentinHistone AcetyltransferasesHistonesKAT7 protein, humanLysineVimentinepithelial-mesenchymal transitionnon-histone acetylationtumorigenesis

Identifiers

PMID37424170
PMCPMC10477884
OpenAlexW4383695321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.