Evidence map›Paper›PMID 37422859›Full record

ArticleJournal of anesthesia2023

Incidence of perioperative hypotension in patients undergoing transurethral resection of bladder tumor after oral 5-aminolevulinic acid administration: a retrospective multicenter cohort study.

Yuriko Kondo, Yusuke Nagamine, Nanako Yoshikawa, Noriyuki Echigo, Tatsuya Kida, Masakazu Sumitomo, Megumi Yoshida, Gaku Inagawa, Takahisa Goto

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of anesthesia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yuriko KondoDepartment of Anesthesiology, Yokohama Rosai Hospital, 3211 Kodukuecho, Kouhoku-Ku, Yokohama, Kanagawa, 222-0036, Japan.
Yusuke NagamineDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, 3-9 Fukuura, Kanazawa-Ku, Yokohama, Kanagawa, 236-0004, Japan. ynagamin@yokohama-cu.ac.jp.ORCID http://orcid.org/0000-0002-0443-5007
Nanako YoshikawaDepartment of Anesthesiology, Yokohama Rosai Hospital, 3211 Kodukuecho, Kouhoku-Ku, Yokohama, Kanagawa, 222-0036, Japan.
Noriyuki EchigoDepartment of Anesthesiology, Yokohama Rosai Hospital, 3211 Kodukuecho, Kouhoku-Ku, Yokohama, Kanagawa, 222-0036, Japan.
Tatsuya KidaDepartment of Anesthesiology, Yokosuka Kyosai Hospital, 1-16 Yonegahama-Dori, Yokosuka, Kanagawa, 238-8558, Japan.
Masakazu SumitomoDepartment of Anesthesiology, Yokosuka Kyosai Hospital, 1-16 Yonegahama-Dori, Yokosuka, Kanagawa, 238-8558, Japan.
Megumi YoshidaDepartment of Anesthesiology, Yokohama Municipal Citizen's Hospital, 1-1 Mitsuzawa Nishimachi, Kanagawa-Ku, Yokohama, Kanagawa, 221-0855, Japan.
Gaku InagawaDepartment of Anesthesiology, Yokohama Municipal Citizen's Hospital, 1-1 Mitsuzawa Nishimachi, Kanagawa-Ku, Yokohama, Kanagawa, 221-0855, Japan.
Takahisa GotoDepartment of Anesthesiology and Critical Care Medicine, Yokohama City University Hospital, 3-9 Fukuura, Kanazawa-Ku, Yokohama, Kanagawa, 236-0004, Japan.
Yokohama Rosai Hospital · JPYokohama City University Hospital · JPYokohama Municipal Citizen's Hospital · JPYokosuka Kyosai Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTumors can be visualized using 5-Aminolevulinic acid hydrochloride (5-ALA) during transurethral resection of bladder tumors (TURBT). Hypotension is an adverse effect of 5-ALA; however, its incidence and morbidity rates are unknown. This study aimed to describe the incidence of perioperative hypotension and identify risk factors for hypotension among patients after 5-ALA administration in TURBT.

methodsThis retrospective multicenter cohort study was conducted at three general hospitals in Japan. Adult patients who underwent elective TURBT after 5-ALA administration between April 2018 and August 2020 were included. The primary outcome was the incidence of perioperative hypotension (mean blood pressure < 65 mmHg). The secondary outcomes were the use of vasoactive agents and adverse events, including urgent intensive care unit (ICU) admission. Multivariate logistic regression analysis was performed to investigate risk factors of the incidence of intraoperative hypotension.

resultsThe median age of 261 patients was 73 years. General anesthesia was induced in 252 patients. The intraoperative hypotension was observed in 246 (94.3%) patients. Three patients (1.1%) were urgently admitted to the ICU for continued vasoactive agent use after surgery. All three patients had renal dysfunction. Multivariate logistic regression analysis revealed that general anesthesia was significantly associated with intraoperative hypotension (adjusted odds ratio, 17.94; 95% confidence interval, 3.21-100.81).

conclusionThe incidence of hypotension in patients undergoing TURBT after 5-ALA administration was 94.3%. The incidence of urgent ICU admission with prolonged hypotension was 1.1% in all patients with renal dysfunction. General anesthesia was significantly associated with intraoperative hypotension.

Indexed as

HypotensionKidney DiseasesUrinary Bladder NeoplasmsAdultAgedAminolevulinic AcidCohort StudiesHumansIncidenceRetrospective StudiesTransurethral Resection of BladderAminolevulinic Acid5-Aminolevulinic acidHypotensionTransurethral resection of bladder tumor

Identifiers

PMID37422859
OpenAlexW4383668306

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.