Evidence map›Paper›PMID 37422857›Full record

SynthesisAnnals of nuclear medicine2023

Diagnostic performance of noninvasive imaging using computed tomography, magnetic resonance imaging, and positron emission tomography for the detection of ovarian cancer: a meta-analysis.

Xiaoxiao Li, Luqin Wang, Pengfei Guo, Qiangkun Sun, Yating Zhang, Cheng Chen, Yulong Zhang

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Annals of nuclear medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Comparing the diagnostic efficacy of [Abdominal radiology (New York) · 2025
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Comparison ofAbdominal radiology (New York) · 2024
    Article
  7. The wings of progress: technological and radiopharmaceutical innovations in nuclear medicine.European journal of nuclear medicine and molecular imaging · 2024
    Article
  8. Cancer medicine · 2024
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiaoxiao Li *Department of Thoracic Surgery, The First Affiliated Hospital of China Medical University, Shenyang, China.
Luqin Wang *Anhui Precision Medicine Technology Engineering Laboratory, Hefei, China.
Pengfei GuoDepartment of Bioinformatics, Precedo Pharmaceuticals Co. Ltd, Hefei, China.
Qiangkun SunDepartment of Bioinformatics, Precedo Pharmaceuticals Co. Ltd, Hefei, China.
Yating ZhangDepartment of Bioinformatics, Precedo Pharmaceuticals Co. Ltd, Hefei, China.
Cheng ChenDepartment of Bioinformatics, Precedo Pharmaceuticals Co. Ltd, Hefei, China. chencheng@hmfl.ac.cn.
Yulong ZhangAnhui Precision Medicine Technology Engineering Laboratory, Hefei, China. ylzhang@precedo.cn.
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this meta-analysis was to compare the diagnostic value of noninvasive imaging methods computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) in the detection of ovarian cancer (OC).

methodsPubMed, Embase, and Ovid were comprehensively searched from the date of inception to 31st, March, 2022. Pooled sensitivity, specificity, positive likelihood ratio (+ LR), negative likelihood ratio (- LR), diagnostic odds ratio (DOR), and area under the curve (AUC) of summary receiver operating characteristic (SROC) with their respective 95% confidence intervals (CIs) were calculated.

resultsSixty-one articles including 4284 patients met the inclusion criteria of this study. Pooled estimates of sensitivity, specificity, and AUC of SROC with respective 95% CIs of CT on patient level were 0.83 (0.73, 0.90), 0.69 (0.54, 0.81), and 0.84 (0.80, 0.87). The overall sensitivity, specificity, SROC value with respective 95% CIs of MRI were 0.95 (0.91, 0.97),0.81 (0.76, 0.85), and 0.90 (0.87, 0.92) on patient level. Pooled estimates of sensitivity, specificity, SROC value of PET/CT on patient level were 0.92 (0.88, 0.94), 0.88 (0.83, 0.92), and 0.96 (0.94, 0.97).

conclusionNoninvasive imaging modalities including CT, MRI, PET (PET/CT, PET/MRI) yielded favorable diagnostic performance in the detection of OC. Hybrid implement of different tools (PET/MRI) is more accurate for identifying metastatic OC.

Indexed as

Ovarian NeoplasmsPositron Emission Tomography Computed TomographyFemaleFluorodeoxyglucose F18HumansMagnetic Resonance ImagingPositron-Emission TomographySensitivity and SpecificityTomography, X-Ray ComputedFluorodeoxyglucose F18CTDiagnostic performanceMeta-analysisMRIOvarian cancerPET

Identifiers

PMID37422857
OpenAlexW4383665472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.