Evidence map›Paper›PMID 37421924›Full record

ArticleBiochemical and biophysical research communications2023

Adipocyte NMNAT1 expression is essential for nuclear NAD

Shintaro Yamaguchi, Daiki Kojima, Tooba Iqbal, Shotaro Kosugi, Michael P Franczyk, Nathan Qi, Yo Sasaki, Keisuke Yaku, Kenji Kaneko, Kenichiro Kinouchi and 4 more

Open access · greenAbstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Shintaro YamaguchiDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan; Center for Human Nutrition, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Daiki KojimaDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.
Tooba IqbalDepartment of Molecular and Medical Pharmacology, Faculty of Medicine, University of Toyama, Toyama, Toyama, 930-0194, Japan.
Shotaro KosugiDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.
Michael P FranczykCenter for Human Nutrition, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Nathan QiDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, 48109, USA.
Yo SasakiDepartment of Genetics, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Keisuke YakuDepartment of Molecular and Medical Pharmacology, Faculty of Medicine, University of Toyama, Toyama, Toyama, 930-0194, Japan.
Kenji KanekoDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.
Kenichiro KinouchiDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.
Hiroshi ItohDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.
Kaori HayashiDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.
Takashi NakagawaDepartment of Molecular and Medical Pharmacology, Faculty of Medicine, University of Toyama, Toyama, Toyama, 930-0194, Japan.
Jun YoshinoDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan; Center for Human Nutrition, Washington University School of Medicine, St. Louis, MO, 63110, USA. Electronic address: jyoshino@keio.jp.
Keio University · JPUniversity of Toyama · JPWashington University in St. Louis · USUniversity of Michigan · US

Funding

Michigan Mouse Metabolic Phenotyping CenterU2CDK110768 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELIAS, CAROL FUZETI · 2016 to 2021
$6.2M
Metabolic Phenotyping in Live Models of Obesity and DiabetesU2CDK135066 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Carol Fuzeti Elias · 2023 to 2026
$3.5M
REGULATION OF SYSTEMIC GLUCOSE AND LIPID HOMEOSTASIS BY ADIPOCYTE NAD BIOSYNTHESISR01DK104995 · NIDDK · WASHINGTON UNIVERSITY · PI KLEIN, SAMUEL · 2016 to 2024
$3.5M
NIDDK NIH HHS R01 DK104995NIDDK NIH HHS U2C DK135066
6 · The paper itself

Abstract

Nicotinamide adenine dinucleotide (NAD

Indexed as

AdipocytesEnergy MetabolismNicotinamide-Nucleotide AdenylyltransferaseThermogenesisAdipose Tissue, BrownAdipose Tissue, WhiteAnimalsDiet, High-FatMiceMice, KnockoutNicotinamide-Nucleotide AdenylyltransferaseNmnat1 protein, mouseAdipose tissueEnergy metabolismNAD(+)NMNAT1NucleusThermogenesis

Identifiers

PMID37421924
PMCPMC12853836
OpenAlexW4383070249

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.