Evidence map›Paper›PMID 37421567›Full record

ArticleJournal of fluorescence2024

Fluorescent Properties of Cyanine Dyes As a Matter of the Environment.

Fan Fan, Vladimir A Povedailo, Ivan L Lysenko, Tatsiana P Seviarynchyk, Olga L Sharko, Ilya O Mazunin, Vadim V Shmanai

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. [European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fan FanInstitute of Physical Organic Chemistry, National Academy of Sciences of Belarus, 13 Surganova str., 220072, Minsk, Belarus.
Vladimir A PovedailoB.I. Stepanov Institute of Physics, National Academy of Sciences of Belarus, 68 Nezavisimost' Ave., 220072, Minsk, Belarus.
Ivan L LysenkoInstitute of Physical Organic Chemistry, National Academy of Sciences of Belarus, 13 Surganova str., 220072, Minsk, Belarus.
Tatsiana P SeviarynchykInstitute of Physical Organic Chemistry, National Academy of Sciences of Belarus, 13 Surganova str., 220072, Minsk, Belarus.
Olga L SharkoInstitute of Physical Organic Chemistry, National Academy of Sciences of Belarus, 13 Surganova str., 220072, Minsk, Belarus.
Ilya O MazuninCenter for Molecular and Cellular Biology, Skolkovo Institute of Science and Technology, Moscow, Russia.
Vadim V ShmanaiInstitute of Physical Organic Chemistry, National Academy of Sciences of Belarus, 13 Surganova str., 220072, Minsk, Belarus. shmanai@ifoch.bas-net.by.

Funding

Belarusian Republican Foundation for Fundamental Research X23RNF-041Russian Science Foundation 23-45-10010The Fund of China Scholarship Council 202008400011
6 · The paper itself

Abstract

In non-viscous aqueous solutions, the cyanine fluorescent dyes Cy3 and Cy5 have rather low fluorescence efficiency (the fluorescence quantum yields of Cy3 and Cy5 are 0.04 and 0.3, respectively [1, 2]) and short excited state lifetimes due to their structural features. In this work, we investigated the effect of solubility and rotational degrees of freedom on the fluorescence efficiency of Cy3 and Cy5 in several ways. We compared the fluorescence efficiencies of two cyanine dyes sCy3 and sCy5 with the introduction of a sulfonyl substituent in the aromatic ring as well as covalently bound to T10 oligonucleotides. The results show that because of the different lengths of the polymethine chains between the aromatic rings of the dyes, cis-trans-isomerization has a much greater effect on the Cy3 molecule than on the Cy5 molecule, while the effect of aggregation is also significant.

Indexed as

Click chemistryCyanine dyesFluorescence intensityFluorescence lifetimeFluorescence quantum yields

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.