Evidence map›Paper›PMID 37421501›Full record

ArticleMagma (New York, N.Y.)2023

High-field magnetic resonance microscopy of aortic plaques in a mouse model of atherosclerosis.

Rita Castro, Sean Gullette, Courtney Whalen, Floyd J Mattie, Ximing Ge, A Catharine Ross, Thomas Neuberger

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Rita CastroDepartment of Nutritional Sciences, Penn State University, PA, 16802, University Park, USA.
Sean GulletteHuck Institutes of The Life Sciences, Penn State University, PA, 16802, University Park, USA.
Courtney WhalenDepartment of Nutritional Sciences, Penn State University, PA, 16802, University Park, USA.
Floyd J MattieDepartment of Nutritional Sciences, Penn State University, PA, 16802, University Park, USA.
Ximing GeDepartment of Nutritional Sciences, Penn State University, PA, 16802, University Park, USA.
A Catharine RossDepartment of Nutritional Sciences, Penn State University, PA, 16802, University Park, USA.
Thomas NeubergerHuck Institutes of The Life Sciences, Penn State University, PA, 16802, University Park, USA. tun3@psu.edu.ORCID http://orcid.org/0000-0002-3965-9780
Pennsylvania State University · US

Funding

Vitamin A Supplementation and Retinol Metabolism in the Neonatal PeriodR01HD066982 · NICHD · PENNSYLVANIA STATE UNIVERSITY, THE · PI ROSS, A. CATHARINE · 2010 to 2019
$2.9M
Molecular Regulation of LRAT and CYP26 in Lung and LiverR01CA090214 · NCI · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI ROSS, A. CATHARINE · 2001 to 2012
$2.6M
NCI NIH HHS R01 CA090214NICHD NIH HHS R01 HD066982
6 · The paper itself

Abstract

objectivesPre-clinical models of human atherosclerosis are extensively used; however, traditional histological methods do not allow for a holistic view of vascular lesions. We describe an ex-vivo, high-resolution MRI method that allows the 3 dimensional imaging of the vessel for aortic plaque visualization and quantification. MATERIALS AND

methodsAortas from apolipoprotein-E-deficient (apoE

resultsA resolution up to 15 × 10x10 μm DISCUSSION: 14 T MR microscopy provided histology-like details of pathologically relevant vascular lesions. This work may provide the path research needs to take to enable plaque characterization in clinical applications.

Indexed as

AtherosclerosisPlaque, AtheroscleroticAnimalsAortaHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMiceMicroscopyAtherosclerotic plaqueEx-vivo MRIMR microscopyPlaque burden

Identifiers

PMID37421501
PMCPMC10667155
OpenAlexW4383621787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.