Evidence map›Paper›PMID 37421430›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2023

Nanocargos designed with synthetic and natural polymers for ovarian cancer management.

Sharon Sofini Ps, Arina Guha, Balasubramanian Deepika, Saranya Udayakumar, Moupriya Nag, Dibyajit Lahiri, Agnishwar Girigoswami, Koyeli Girigoswami

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sharon Sofini PsMedical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Chettinad Health City, Rajiv Gandhi Salai, Kelambakkam, Tamil Nadu, 603103, India.ORCID http://orcid.org/0000-0003-1109-1705
Arina GuhaDept. of Biotechnology, University of Engineering & Management, Kolkata, 700160, West Bengal, India.ORCID http://orcid.org/0009-0002-3702-7461
Balasubramanian DeepikaMedical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Chettinad Health City, Rajiv Gandhi Salai, Kelambakkam, Tamil Nadu, 603103, India.ORCID http://orcid.org/0000-0003-4441-7863
Saranya UdayakumarMedical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Chettinad Health City, Rajiv Gandhi Salai, Kelambakkam, Tamil Nadu, 603103, India.ORCID http://orcid.org/0009-0003-3655-4689
Moupriya NagDept. of Biotechnology, University of Engineering & Management, Kolkata, 700160, West Bengal, India.ORCID http://orcid.org/0000-0002-1365-5722
Dibyajit LahiriDept. of Biotechnology, University of Engineering & Management, Kolkata, 700160, West Bengal, India.ORCID http://orcid.org/0000-0002-9968-6078
Agnishwar GirigoswamiMedical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Chettinad Health City, Rajiv Gandhi Salai, Kelambakkam, Tamil Nadu, 603103, India.ORCID http://orcid.org/0000-0003-0475-2544
Koyeli GirigoswamiMedical Bionanotechnology, Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Chettinad Health City, Rajiv Gandhi Salai, Kelambakkam, Tamil Nadu, 603103, India. koyelig@gmail.com.ORCID http://orcid.org/0000-0003-1554-5241
Chettinad Academy of Research and Education · INUniversity of Engineering & Management · IN

Funding

Chettinad Academy of Research and Education 004/Regr./AR-Research/2022-06
6 · The paper itself

Abstract

Ovarian cancer cells usually spread in the peritoneal region, and if chemotherapeutic drugs can be given in these regions with proximity, then the anticancer property of the chemotherapeutic drugs can enhance. However, chemotherapeutic drug administrations are hindered by local toxicity. In the drug delivery system, microparticles or nanoparticles are administered in a controlled manner. Microparticles stay in a close vicinity while nanoparticles are smaller and can move evenly in the peritoneum. Intravenous administration of the drug evenly distributes the medicine in the target places and if the composition of the drug has nanoparticles it will have more specificity and will have easy access to the cancer cells and tumors. Among the different types of nanoparticles, polymeric nanoparticles were proven as most efficient in drug delivery. Polymeric nanoparticles are seen to be combined with many other molecules like metals, non-metals, lipids, and proteins, which helps in the increase of cellular uptake. The efficiency of different types of polymeric nanoparticles used in delivering the load for management of ovarian cancer will be discussed in this mini-review.

Indexed as

Antineoplastic AgentsNanoparticlesOvarian NeoplasmsDrug Delivery SystemsFemaleHumansPolymersAntineoplastic AgentsPolymersBionanotechnologyNano-enabled drug deliveryNatural polymersOvarian cancerSynthetic polymers

Identifiers

PMID37421430
OpenAlexW4383620749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.