Evidence map›Paper›PMID 37421322›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2023

Daytime autonomic nervous system functions differ among adults with and without insomnia symptoms.

William V McCall, Stephen W Looney, Maria Zulfiqar, Evan Ketcham, Megan Jones, Carter Mixson, Laryssa McCloud, Brian J Miller, Peter B Rosenquist

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In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Objectively short sleep predicts incidence of cardiac and cerebrovascular events.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

William V McCallDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, Georgia.
Stephen W LooneyDepartment of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, Georgia.
Maria ZulfiqarDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, Georgia.
Evan KetchamDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, Georgia.
Megan JonesDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, Georgia.
Carter MixsonDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, Georgia.
Laryssa McCloudDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, Georgia.
Brian J MillerDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, Georgia.
Peter B RosenquistDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta University, Augusta, Georgia.
Augusta University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesWe gathered data to determine whether daytime assays of the autonomic nervous system would differ between persons with no vs modest insomnia symptoms and would correlate with the severity of insomnia symptoms in patients.

methodsThis report is composed of 2 studies. Study 1 conducted pupillary light reflex (PLR) measurements in community volunteers who were not seeking medical care. Study 2 contrasted PLR and heart rate variability in a different sample of community volunteers and a comparison sample of adults seeking outpatient care for insomnia and psychiatric problems. All measurements were taken between 3 and 5 pm.

resultsIn Study 1, volunteers with modest insomnia symptom severity had a more rapid PLR average constriction velocity compared with those with no symptoms. In Study 2, lower heart rate variability, indicating higher levels of physiologic arousal, generally were in agreement with faster PLR average constriction velocity, both of which indicate higher levels of arousal. Insomnia symptom severity was highly correlated with faster average constriction velocity in the patient sample.

conclusionsThese studies suggest that (1) daytime measurements of the autonomic nervous system differ between persons with modest vs no insomnia symptoms and (2) insomnia symptom severity is highly correlated with PLR. Daytime measurement of autonomic nervous system activity might allow for daytime point-of-care measurement to characterize the level of physiologic arousal to define a hyperarousal subtype of insomnia disorder. CITATION: McCall WV, Looney SW, Zulfiqar M, et al. Daytime autonomic nervous system functions differ among adults with and without insomnia symptoms.

Indexed as

Sleep Initiation and Maintenance DisordersAdultArousalAutonomic Nervous SystemHumansarousalautonomic nervous systemheart rate variabilityinsomniapupillary light reflex

Identifiers

PMID37421322
PMCPMC10620659
OpenAlexW4383652607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.