Evidence map›Paper›PMID 37421282›Full record

ArticleJournal of the American Heart Association2023

Positive Airway Pressure Therapy Adherence and Health Care Resource Use in Patients With Obstructive Sleep Apnea and Heart Failure With Preserved Ejection Fraction.

Peter A Cistulli, Atul Malhotra, Kate V Cole, Anita S Malik, Jean-Louis Pépin, Fatima H Sert Kuniyoshi, Adam V Benjafield, Virend K Somers, medXcloud group *

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Acute Heart Failure and Central Sleep Apnea.Sleep medicine clinics · 2025
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Breathe Better and Preserve Heart.Journal of the American Heart Association · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Peter A CistulliCharles Perkins Centre, Faculty of Medicine and Health University of Sydney Australia.ORCID 0000-0002-7920-4924
Atul MalhotraUniversity of California San Diego La Jolla CA USA.ORCID 0000-0002-9509-1827
Kate V ColeResMed Science Center San Diego CA USA.ORCID 0000-0001-9008-9229
Anita S MalikResMed Science Center San Diego CA USA.ORCID 0000-0002-2592-2912
Jean-Louis PépinInstitut National de la Santé et de la Recherche Médicale (INSERM) U 1300, HP2 Laboratory (Hypoxia: Pathophysiology), Grenoble Alpes University Grenoble France.ORCID 0000-0003-3832-2358
Fatima H Sert KuniyoshiResMed Science Center San Diego CA USA.ORCID 0000-0001-7644-7384
Adam V BenjafieldResMed Science Centre Sydney Australia.ORCID 0000-0003-4716-2827
Virend K SomersDepartment of Cardiovascular Medicine Mayo Clinic Rochester MN USA.ORCID 0000-0003-4045-4341
medXcloud group *
Inserm · FRMayo Clinic · USResMed (Australia) · AUResMed (United States) · USThe University of Sydney · AUUniversity of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Obstructive sleep apnea (OSA) is common in heart failure with preserved ejection fraction (HFpEF). However, current evidence is equivocal regarding the potential benefits of treating OSA with positive airway pressure (PAP) therapy in HFpEF. This study assessed the association between adherence to PAP therapy and health care resource use in patients with OSA and HFpEF. Methods and Results Administrative insurance claims data linked with objective PAP therapy usage data from patients with OSA and HFpEF were used to determine associations between PAP adherence and a composite outcome including hospitalizations and emergency room visits. One-year PAP adherence was based on an adapted US Medicare definition. Propensity score methods were used to create groups with similar characteristics across PAP adherence levels. The study cohort included 4237 patients (54.0% female, mean age 64.1 years); 40% were considered adherent to PAP therapy (30% intermediate adherent, 30% nonadherent). In the matched cohort, PAP-adherent patients had fewer health care resource use visits than nonadherent patients, a 57% decrease in hospitalizations, and a 36% decrease in emergency room visits versus the year before PAP initiation. Total health care costs were lower in adherent patients than nonadherent patients ($12 732 versus $15 610,

Indexed as

Heart FailureSleep Apnea, ObstructiveAgedContinuous Positive Airway PressureFemaleHealth Care CostsHumansMaleMedicareMiddle AgedPatient ComplianceRetrospective StudiesStroke VolumeUnited Stateshealth care resource useheart failureobstructive sleep apneapositive airway pressure adherence

Identifiers

PMID37421282
PMCPMC10382094
OpenAlexW4383619186

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.